中医经典理论和临床实践论治盐敏感性高血压病-HKRCMP.docVIP

中醫經典理論和臨床實踐論治鹽敏感性高血壓病 　劉樊1 周宜1 張莉2 趙雲龍1 （1、成都中醫藥大學基礎醫學院黃帝內經專業，成都610075；2、成都市第一人民醫院，成都610016） 【摘要】 目的：根據《黃帝內經》「鹹入腎」的理論，結合中醫治療鹽敏感性高血壓的臨床實踐，探索鹽敏感性高血壓的病因病機，以及中醫方藥治療鹽敏感性高血壓的方法。方法：從《黃帝內經》「鹹入腎」的理論，歸納高鹽損腎是鹽敏感性高血壓的重要病因，並進一步根據臨床實踐，以及現代醫學對鹽敏感性高血壓的認識，分析了鹽敏感性高血壓的病因病理，並歸納總結了治療高血壓的補腎方藥及其有效成份。結果：根據高鹽損腎的中醫理論以及現代醫學研究得到的腎臟存在的遺傳缺陷，證實了鹽敏感性高血壓最早應該損害腎臟，據此提出了對鹽敏感性高血壓應採取補腎為主的治療原則。結論：腎虛是鹽敏感性高血壓的重要病因，中醫運用補腎方藥來預防和治療鹽敏感性高血壓具有廣闊的前景。 【關鍵詞】鹽敏感高血壓病腎治療 The Classic Theory and Clinic Practice on treatment variation for Salt-sensitive Hypertension Liu Fan1Zhou Yi1*ZhangLi2Zhao yun-long1 (1.Chengdu University of TCM, 610075; 2.The First People’s Hospital of Chengdu, China, 610016) [Abstract]: Objective: According to the theory of salt belongs to kidney and clinical experience of treating salt-sensitive high blood pressure (HBP) in Chinese medicine, the aim of this study is to investigate the pathogenesis of salt-sensitive high blood pressure and treatments in traditional Chinese medicine for this disease. Methods: Concluding the pathogenesis of salt-sensitive high blood pressure might due to too much salt harms kidney based on the theory of salt belongs to kidney in Huangdis Classic, and summarize the active ingredients for treating HBP. Results: On the basis of the theory that kidney get harmed by too much salt and the evidence of congenital defect in the kidney, we prove that salt-sensitive high blood pressure damaged kidney firstly, and make the therapeutic principle given first place to tonify kidney. Conclusion: Deficiency of the kidney leads to salt-sensitive high blood pressure. tonifying kidney has a extensive prospect at preventing and treating salt-sensitive high blood pressure. [Keywords]: Salt-sensitive; Hypertension; Kidney; Treatment. 1 鹽敏感性高血壓與腎虛的關係 1.1 中醫的相關傳統理論 《素問?宣明五氣篇》：「五味所入……鹹入腎。」鹹為五味之一，根據同氣相求的原則，鹹味入水臟—腎。所以，一方面，氣受鹹味的滋養，如《素問?陰陽應象大論》：「水生鹹，鹹生腎。」另一方面，腎臟又是鹹味藥物所「喜攻」之臟，「鹹味湧泄」，而腎主閉藏，氣貴固密。所以過食鹹味又最易損傷到腎。 《素問?古天真論》曰「腎者主水。」《素問?逆調論》曰：「腎者水藏，主津液。」這與現代醫學腎臟作為泌尿器官的生理功能是一致的。而目前，大量科學研究也是用現代醫學腎臟的病理變