detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy检测血液中改变转录组存在公开经过两个星期的治疗.pdfVIP

detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy检测血液中改变转录组存在公开经过两个星期的治疗.pdf

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detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy检测血液中改变转录组存在公开经过两个星期的治疗

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy 1 1 1,3 2,4 4,5 Chloe I. Bloom *, Christine M. Graham , Matthew P. R. Berry , Katalin A. Wilkinson , Tolu Oni , 1 6 6 6,7 6 Fotini Rozakeas , Zhaohui Xu , Jose Rossello-Urgell , Damien Chaussabel , Jacques Banchereau , 6 8 2,4,5 1 Virginia Pascual , Marc Lipman , Robert J. Wilkinson , Anne O’Garra 1 Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom, 2 Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom, 3 Department of Respiratory Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom, 4 Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa, 5 Department of Medicine, Wright Fleming Institute, Imperial College, London, United Kingdom, 6 Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America, 7 Systems Immunology, Benaroya Research Institute, Seattle, Washington, United States of America, 8 Department of Thoracic Medicine, Royal Free Hospital NHS Trust, London, United Kingdom Abstract Rationale: Globally there are approximately 9 million new active tuberculosis cases and 1.4 million deaths annually. Effective antituberculosis treatment monitoring is

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