detection of a cis eqtl controlling bmco1 gene expression leads to the identification of a qtg for chicken breast meat color检测的cis eqtl bmco1控制基因表达导致识别的qtg鸡胸肉的颜色.pdfVIP
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detection of a cis eqtl controlling bmco1 gene expression leads to the identification of a qtg for chicken breast meat color检测的cis eqtl bmco1控制基因表达导致识别的qtg鸡胸肉的颜色
Detection of a Cis eQTL Controlling BMCO1 Gene Expression Leads to the Identification of a QTG for Chicken Breast Meat Color 1 1 ´ 1 ´ ´ 2 ˆ 3 Elisabeth Le Bihan-Duval *, Javad Nadaf , Cecile Berri , Frederique Pitel , Benoıt Graulet , Estelle 1 2 4,5 4,5 ´ 4,5 Godet , Sophie Y. Leroux , Olivier Demeure , Sandrine Lagarrigue , Cecile Duby , Larry A. Cogburn6, Catherine M. Beaumont1, Michel J. Duclos 1 ´ ´ 1 INRA, UR83, Recherches Avicoles, Nouzilly, France, 2 INRA, ENVT, UMR444 Genetique Cellulaire, Castanet-Tolosan, France, 3 INRA, UR1213 Herbivores, Centre de ` ´ ´ ´ ´ Clermont-Ferrand/Theix, St-Genes-Champanelle, France, 4 INRA, UMR 598 Genetique Animale, Rennes, France, 5 Agrocampus Ouest, UMR 598 Genetique Animale, Rennes, France, 6 Department of Animal and Food Sciences, University of Delaware, Newark, Delaware, United States of America Abstract Classical quantitative trait loci (QTL) analysis and gene expression QTL (eQTL) were combined to identify the causal gene (or QTG) underlying a highly significant QTL controlling the variation of breast meat color in a F2 cross between divergent high- growth (HG) and low-growth (LG) chicken lines. Within this meat quality QTL, BCMO1 (Accession number GenBank: AJ271386), encoding the b-carotene 15, 159-monooxygenase, a key enzyme
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