deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia赤字长期识别记忆显示分离亚型在先天性面容失认症.pdfVIP
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deficits in long-term recognition memory reveal dissociated subtypes in congenital prosopagnosia赤字长期识别记忆显示分离亚型在先天性面容失认症
Deficits in Long-Term Recognition Memory Reveal Dissociated Subtypes in Congenital Prosopagnosia 1 ¨ 1,2 1 3 Rainer Stollhoff *, Jurgen Jost , Tobias Elze , Ingo Kennerknecht 1 Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany, 2 Santa Fe Institute for the Sciences of Complexity, Santa Fe, New Mexico, United States of ¨ ¨ ¨ America, 3 Institute of Human Genetics, Westfalische Wilhelms-Universitat, Munster, Germany Abstract The study investigates long-term recognition memory in congenital prosopagnosia (CP), a lifelong impairment in face identification that is present from birth. Previous investigations of processing deficits in CP have mostly relied on short-term recognition tests to estimate the scope and severity of individual deficits. We firstly report on a controlled test of long-term (one year) recognition memory for faces and objects conducted with a large group of participants with CP. Long-term recognition memory is significantly impaired in eight CP participants (CPs). In all but one case, this deficit was selective to faces and didn’t extend to intra-class recognition of object stimuli. In a test of famous face recognition, long-term recognition deficits were less pronounced, even after accounting for differences in media consumption between controls and CPs. Secondly, we combined test results on long-term and short-term recognition of faces and objects, and found a large heterogeneity in severity and scope of individual deficits. Analysis of the observed heterogeneity revealed a dissociation of CP into subtypes with a homogeneous phenotypical profile. Thirdly,
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