有哪些信誉好的足球投注网站correlation of group c meningococcal conjugate vaccine response with b- and t-lymphocyte activity的相关性与b - c群脑膜炎球菌结合疫苗反应和早期活动.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
correlation of group c meningococcal conjugate vaccine response with b- and t-lymphocyte activity的相关性与b - c群脑膜炎球菌结合疫苗反应和早期活动
Correlation of Group C Meningococcal Conjugate Vaccine Response with B- and T-Lymphocyte Activity 1 1 2,3 2,3 2 4 James B. Wing , Lynne Smart , Ray Borrow , Jamie Findlow , Helen Findlow , Andrew Lees , Robert C. Read1*, Andrew W. Heath1 1 Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom, 2 Vaccine Evaluation Unit, Health Protection Agency, Manchester Royal Infirmary, Manchester, United Kingdom, 3 Inflammation Sciences Research Group, University of Manchester, Manchester, United Kingdom, 4 Fina Biosolutions LLC, Rockville, Maryland, United States of America Abstract Despite the success of conjugate vaccination against meningococcal group C (MenC) disease, post-vaccination, some individuals still exhibit rapid waning of initially protective bactericidal antibody levels. The mechanism of this relative loss of humoral protection remains undetermined. In this report we have investigated the relationship between T- and B-cell activation and co-stimulation and the loss of protective antibody titers. We have found that healthy volunteers who lose protective MenC antibody levels one year after receipt of glycoconjugate vaccine exhibit no detectable cellular defect in polyclonal B- or T-cell activation, proliferation or the B-memory pool. This suggests that the processes underlying the more rapid loss of antibody levels are independent of defects in either initial T- or B-cell activation. Citation: Wing JB, Smart L, Borrow R, Findlow J, Findlow H, et al. (2012) Correlation of Group C Meningococcal Conjugate Vaccine Response with B- and T- Lymphocyte Activity. PLoS ONE 7(2): e31160. doi:10.1371/journal.pone.0031160
您可能关注的文档
- computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton implications for side effects of general anesthesia计算预测的挥发性麻醉剂与微管细胞骨架的交互对全身麻醉的副作用的影响.pdf
- computer controlled automated assay for comprehensive studies of enzyme kinetic parameters计算机控制自动分析综合酶动力学参数的研究.pdf
- computationally-optimized bone mechanical modeling from high-resolution structural imagescomputationally-optimized骨机械建模从高分辨率结构图像.pdf
- computer-aided diagnosis systems for brain diseases in magnetic resonance images计算机辅助诊断系统的脑部疾病的磁共振图像.pdf
- computation emerges from adaptive synchronization of networking neurons计算中自适应神经元网络的同步.pdf
- computing the szeged and pi indices of vc5c7[p,q] and hc5c7[p,q] nanotubes计算vc5c7的塞格德和π指数(p,q)和hc5c7(p,q)纳米管.pdf
- computing the partition function for kinetically trapped rna secondary structures计算活动困rna二级结构的配分函数.pdf
- computing the topological entropy of multimodal maps via min-max sequences计算多通道通过min-max序列映射的拓扑熵.pdf
- comt val158met polymorphism and neural pain processingcomt val158met多态性和神经疼痛处理.pdf
- computing the viscosity of supercooled liquids markov network model计算过冷液体的粘度马尔可夫网络模型.pdf
- correlation of memory t cell responses against trap with protection from clinical malaria, and cd4+ cd25high t cells with susceptibility in kenyans记忆t细胞反应的相关性对陷阱与临床疟疾、保护和cd4 + t细胞cd25high易感性在肯尼亚人.pdf
- correlation of the rates of solvolysis of neopentyl chloroformate—a recommended protecting agent相关的溶剂分解率的新戊基chloroformate-a建议保护代理.pdf
- correlation of the rates of solvolysis of i-butyl fluoroformate and a consideration of leaving-group effects的溶剂分解率的相关性i-butyl fluoroformate和考虑的离去基团的影响.pdf
- correlation of humoral immune response in southern bluefin tuna, t. maccoyii, with infection stage of the blood fluke, cardicola forsteri体液免疫反应的相关性在南方蓝鳍金枪鱼,t . maccoyii与血吸虫的感染阶段、cardicola forsteri.pdf
- correlation of the rates of solvolysis of two arenesulfonyl chlorides and of trans-β-styrenesulfonyl chloride — precursors in the development of new pharmaceuticals的溶剂分解率的相关性两个arenesulfonyl氯化物和氯化trans-β-styrenesulfonylu2014u2014在开发新药物前体.pdf
- correlation of membrane binding and hydrophobicity to the chaperone-like activity of pdc-109, the major protein of bovine seminal plasma相关的绑定和疏水性膜的chaperone-like活动pdc - 109,牛精浆的主要蛋白质.pdf
- correlations of the specific rates of solvolysis of aromatic carbamoyl chlorides, chloroformates, chlorothionoformates, and chlorodithioformates revisited芳香的特定的溶剂分解率的相关性[氨基甲酰氯,氯甲酸酯,chlorothionoformates,chlorodithioformates再现.pdf
- corresponding mitochondrial dna and niche divergence for crested newt candidate species相应的线粒体dna和小众冠候选人纽特物种的差异.pdf
- corrosion protection of electrically conductive surfaces导电表面的腐蚀保护.pdf
- correlation of the growth rate of the hydrate layer at a guestliquid-water interface to mass transfer resistance相关的增长率水合物层guestliquid-water界面传质阻力.pdf
文档评论（0）