comparing gis-based measures in access to mammography and their validity in predicting neighborhood risk of late-stage breast cancer基于gis技术比较获得乳房x光检查措施及其有效性在预测社区晚期乳腺癌的风险.pdfVIP
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comparing gis-based measures in access to mammography and their validity in predicting neighborhood risk of late-stage breast cancer基于gis技术比较获得乳房x光检查措施及其有效性在预测社区晚期乳腺癌的风险
Comparing GIS-Based Measures in Access to Mammography and Their Validity in Predicting Neighborhood Risk of Late-Stage Breast Cancer Min Lian*, James Struthers, Mario Schootman Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America Abstract Background: Assessing neighborhood environment in access to mammography remains a challenge when investigating its contextual effect on breast cancer-related outcomes. Studies using different Geographic Information Systems (GIS)-based measures reported inconsistent findings. Methods: We compared GIS-based measures (travel time, service density, and a two-Step Floating Catchment Area method [2SFCA]) of access to FDA-accredited mammography facilities in terms of their Spearman correlation, agreement (Kappa) and spatial patterns. As an indicator of predictive validity, we examined their association with the odds of late-stage breast cancer using cancer registry data. Results: The accessibility measures indicated considerable variation in correlation, Kappa and spatial pattern. Measures using shortest travel time (or average) and service density showed low correlations, no agreement, and different spatial patterns. Both types of measures showed low correlations and little agreement with the 2SFCA measures. Of all measures, only the two measures using 6-timezone-weighted 2SFCA method were associated with increased odds of late-stage breast cancer (quick-distance-decay: odds ratio [OR] = 1.15, 95% confidence interval [CI] = 1.01–1.32; slow-distance-decay: OR = 1.19, 95% CI = 1.03–1.37) after controlling for demographics and neighborhood socioeconomic deprivation. Conclusions: Various GIS-based measures of access to mammography facilities exist and are not identical in principle and their association with late-stage breast cancer ris
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