comparative proteomic analysis of serum from patients with systemic sclerosis and sclerodermatous gvhd. evidence of defective function of factor h比较蛋白质组学分析系统性硬化患者的血清和sclerodermatous gvhd。.pdfVIP

Comparative Proteomic Analysis of Serum from Patients with Systemic Sclerosis and Sclerodermatous GVHD. Evidence of Defective Function of Factor H 1 1 2 1 1 Cinzia Scambi *, Valentina La Verde , Lucia De Franceschi , Giovanni Barausse , Fabio Poli , Fabio 3 3 4 5 6 7 Benedetti , Marco Sorio , Francesca Deriu , Paola Roncada , Oscar Bortolami , Francesco Turrini , Paola 1 1 1 1 Caramaschi , Chiara Stranieri , Lisa M. Bambara , Domenico Biasi 1 Section of Rheumatology, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy, 2 Section of Internal Medicine, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy, 3 Section of Haematology, Department of Clinical and Experimental Medicine, University of Verona, Verona, Italy, 4 Department of Veterinary Pathology, Hygiene and Public Health (DIPAV), University of Milano, Milano, Italy, 5 Section of Proteomics, Istituto Sperimentale Italiano L. Spallanzani, University of Milano, Milano, Italy, 6 Unit of Epidemiology and Medical Statistics, Department of Medicine and Public Health, University of Verona, Verona, Italy, 7 Section of Medical Chemistry, Department of Genetic, Biological and Medical Chemistry, University of Torino, Torino, Italy Abstract Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by immunological and vascular abnormalities. Until now, the cause of SSc remains unclear. Sclerodermatous graft-versus-host disease (ScGVHD) is one of the most severe complications following bone marrow