有哪些信誉好的足球投注网站comparative proteomics of inner membrane fraction from carbapenem-resistant acinetobacter baumannii with a reference strain内膜分数的比较蛋白质组学从特拉鲍曼不动杆菌与应变的引用.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
comparative proteomics of inner membrane fraction from carbapenem-resistant acinetobacter baumannii with a reference strain内膜分数的比较蛋白质组学从特拉鲍曼不动杆菌与应变的引用
Comparative Proteomics of Inner Membrane Fraction from Carbapenem-Resistant Acinetobacter baumannii with a Reference Strain 1 1 2 1 Vishvanath Tiwari , Jitendraa Vashistt , Arti Kapil , Rajeswari R. Moganty * 1 Department of Biochemistry, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 2 Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India Abstract Acinetobacter baumannii has been identified by the Infectious Diseases Society of America as one of the six pathogens that cause majority of hospital infections. Increased resistance of A. baumannii even to the latest generation of b-lactams like carbapenem is an immediate threat to mankind. As inner-membrane fraction plays a significant role in survival of A. baumannii, we investigated the inner-membrane fraction proteome of carbapenem-resistant strain of A. baumannii using Differential In-Gel Electrophoresis (DIGE) followed by DeCyder, Progenesis and LC-MS/MS analysis. We identified 19 over- expressed and 4 down-regulated proteins (fold change.2, p ,0.05) in resistant strain as compared to reference strain. Some of the upregulated proteins in resistant strain and their association with carbapenem resistance in A. baumannii are: i) b- lactamases, AmpC and OXA-51: cleave and inactivate carbapenem ii) metabolic enzymes, ATP synthase, malate dehydrogenase and 2-oxoglutarate dehydrogenase: help in increased energy production for the survival and iii) elongation factor Tu and ribosomal proteins: help in the overall protein production. Further, entry of carbapenem perhaps is limited by controlled production of OmpW and low levels of surface antigen help to evade host defence mecha
您可能关注的文档
- blood-based biomarkers for the optimization of anti-angiogenic therapiesblood-based优化抗血管生成疗法的生物标志物.pdf
- blood-based biomarkers of aggressive prostate cancerblood-based侵略性前列腺癌的生物标志物.pdf
- blood glutamate scavenging insight into neuroprotection血液中谷氨酸清除了解神经保护.pdf
- bloodborne viral hepatitis infections among drug users the role of vaccination吸毒者bloodborne病毒性肝炎感染免疫的作用.pdf
- blood pressure variations real-time reflect the conditioned fear learning and memory血压变化实时反映条件性恐惧学习和记忆.pdf
- blue whales respond to anthropogenic noise蓝鲸应对人为噪音.pdf
- blue light acts as a double-edged sword in regulating sexual development of hypocrea jecorina (trichoderma reesei)蓝光作为一把双刃剑在调节性发展hypocrea jecorina(木霉属reesei).pdf
- bloom’s syndrome and pich helicases cooperate with topoisomerase iiα in centromere disjunction before anaphase布鲁姆的综合症和pich解旋酶配合拓扑异构酶iiα在着丝点分裂后期之前.pdf
- blueprint for a high-performance biomaterial full-length spider dragline silk genes蓝图高性能生物材料完整的蜘蛛丝基因.pdf
- bluetongue virus vp1 polymerase activity in vitro template dependency, dinucleotide priming and cap dependency蓝舌病病毒vp1聚合酶活性在体外模板依赖性,二核苷酸启动和帽的依赖.pdf
- comparative qstr study using semi-empirical and first principle methods based descriptors for acute toxicity of diverse organic compounds to the fathead minnow比较qstr使用半经验和第一原理方法研究基于描述符不同有机化合物急性毒性的软.pdf
- comparative omics-driven genome annotation refinement application across yersiniae比较omics-driven基因组注释在yersiniae改进应用程序.pdf
- comparative signature-tagged mutagenesis identifies pseudomonas factors conferring resistance to the pulmonary collectin sp-a比较signature-tagged诱变因素识别假单胞菌产生抗性的肺collectin sp-a.pdf
- comparative silac proteomic analysis of trypanosoma brucei bloodstream and procyclic lifecycle stagessilac比较蛋白质组学分析锥虫属brucei血液和生命周期阶段亦.pdf
- comparative quantitative mass spectrometry analysis of mhc class ii-associated peptides reveals a role of gilt in formation of self-peptide repertoire类ii-associated肽mhc的比较定量质谱分析揭示了一个镀金的角色活动形成的曲目.pdf
- comparative studies of the pyrolytic and kinetic characteristics of maize straw and the seaweed ulva pertusa比较研究玉米秸秆的热解和动力学特征和海藻石莼pertusa.pdf
- comparative structural analysis of lipid binding start domains比较结构分析脂质绑定域名开始.pdf
- comparative proteomic analysis of streptococcus suis biofilms and planktonic cells that identified biofilm infection-related immunogenic proteins比较蛋白质组学分析的链球菌生物膜和浮游细胞识别生物膜感染相关性免疫原性的蛋白质.pdf
- comparative plasma lipidome between human and cynomolgus monkey are plasma polar lipids good biomarkers for diabetic monkeys比较人类和猕猴猴之间的等离子体lipidome等离子体极性脂质好生物标志物糖尿病猴子.pdf
- comparative studies of vertebrate beta integrin genes and proteins ancient genes in vertebrate evolution比较研究脊椎动物基因和蛋白质β整合素古代在脊椎动物进化的基因.pdf
文档评论（0）