有哪些信誉好的足球投注网站combo-fish enables high precision localization microscopy as a prerequisite for nanostructure analysis of genome locicombo-fish使高精度定位显微镜作为纳米结构基因组位点分析的先决条件.pdfVIP
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combo-fish enables high precision localization microscopy as a prerequisite for nanostructure analysis of genome locicombo-fish使高精度定位显微镜作为纳米结构基因组位点分析的先决条件
Int. J. Mol. Sci. 2010, 11, 4094-4105; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article COMBO-FISH Enables High Precision Localization Microscopy as a Prerequisite for Nanostructure Analysis of Genome Loci 1 1 2 2 1 Patrick Müller , Eberhard Schmitt , Anette Jacob , Jörg Hoheisel , Rainer Kaufmann , Christoph Cremer 1 and Michael Hausmann 1,* 1 Kirchhoff-Institute for Physics, Im Neuenheimer Feld 227, 69120 Heidelberg, Germany; E-Mails: muellerp@kip.uni-heidelberg.de (P.M.); eschmitt@kip.uni-heidelberg.de (E.S.); kaufmann@kip.uni-heidelberg.de (R.K.); cremer@kip.uni-heidelberg.de (C.C.) 2 German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany; E-Mails: a.jacob@dkfz.de (A.J.); j.hoheisel@dkfz-heidelberg.de (J.H.) * Author to whom correspondence should be addressed; E-Mail: hausmann@kip.uni-heidelberg.de; Tel.: +49-6221-549-824; Fax: +49-6221-549-112. Received: 15 September 2010; in revised form: 16 October 2010 / Accepted: 18 October 2010 / Published: 21 October 2010 Abstract: With the completeness of genome databases, it has become possible to develop a novel FISH (Fluorescence in Situ Hybridization) technique called COMBO-FISH (COMBinatorial Oligo FISH). In contrast to other FISH techniques, COMBO-FISH m
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