μ-calpain conversion of antiapoptotic bfl-1 (bcl2a1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosisμ-calpain凋亡bfl-1转换(bcl2a1)揭示了两个不同的阿尔法螺旋prodeath因素诱导mitochondria-mediated细胞凋亡.pdfVIP
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μ-calpain conversion of antiapoptotic bfl-1 (bcl2a1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosisμ-calpain凋亡bfl-1转换(bcl2a1)揭示了两个不同的阿尔法螺旋prodeath因素诱导mitochondria-mediated细胞凋亡
m-Calpain Conversion of Antiapoptotic Bfl-1 (BCL2A1) into a Prodeath Factor Reveals Two Distinct alpha- Helices Inducing Mitochondria-Mediated Apoptosis ´ 1. ´ 2. ´ 2 5 ´ 3 Juan Garcıa Valero , Aurelie Cornut-Thibaut , Romain Juge , Anne-Laure Debaud , Diana Gimenez , 6 ´ 5 ´ 3,4 2 2 Germain Gillet , Nathalie Bonnefoy-Berard , Jesus Salgado , Gilles Salles , Abdel Aouacheria , ´ ˆ 2* Jerome Kucharczak ´ ´ ´ 1 Institut de Biologie et Chimie des Proteines (IBCP), CNRS UMR 5086, Universite Lyon 1, IFR 128, Lyon, France, 2 Laboratoire de Biologie Moleculaire de la Cellule (LBMC), ´ Ecole Normale Superieure de Lyon, CNRS UMR 5239, SFR Biosciences Gerland-Lyon Sud US8/UMS3444, Lyon, France, 3 Instituto de Ciencia Molecular, Universidad de ´ ´ ´ Valencia, Paterna (Valencia), Spain, 4 Departamento de Bioquımica y Biologıa Molecular, Universidad de Valencia, Burjassot (Valencia), Spain, 5 Inserm U851, Universite ´ ´ ´ ´ Lyon 1, IFR128, Lyon, France, 6 Centre de recherche en cancerologie de Lyon, Centre Leon Berard, Universite Lyon
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