有哪些信誉好的足球投注网站- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
zeb1 in pancreatic cancerzeb1在胰腺癌
Cancers 2010, 2, 1617-1628; doi:10.3390/cancers2031617 OPEN ACCESS cancers ISSN 2072-6694 /journal/cancers Review ZEB1 in Pancreatic Cancer Ulrich Wellner, Thomas Brabletz and Tobias Keck * Department of General and Visceral Surgery, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany; E-Mails: ulrich.wellner@uniklinik-freiburg.de (U.W.); thomas.brabletz@uniklinik-freiburg.de (T.B.) * Author to whom correspondence should be addressed; E-Mail: tobias.keck@uniklinik-freiburg.de; Tel.: +49-761-270-2808; Fax: +49-761-270-2808. Received: 30 June 2010; in revised form: 16 August 2010 / Accepted: 17 August 2010 / Published: 18 August 2010 Abstract: Pancreatic cancer is one of the most malignant human neoplasias. On the molecular level, epithelial-mesenchymal transition (EMT) has been demonstrated to contribute to the malignant phenotype of pancreatic cancer cells. ZEB1 is a transcriptional repressor that has been identified as an inducer of EMT. A negative feedback loop between ZEB1 and microRNA-200c has been shown to regulate this EMT induction in various models. With respect to pancreatic cancer, primary effects of EMT comprise increased local and distant tumor cell dissemination. Another recently described feature of the EMT is the acquisition of cancer stem cell traits. For pancreatic cancer cells, antagonism between ZEB1 and stemness-inhibiting micro-RNAs has been demonstrated to contribute to this
您可能关注的文档
- whole blood dna aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease a pilot study全血dna异常甲基化在胰腺腺癌显示与疾病的初步研究.pdf
- whole blood interferon-gamma assay for baseline tuberculosis screening among japanese healthcare students全血移行为基线结核病筛查日本医疗学生分析.pdf
- whole body screening using high-temperature superconducting mr volume resonators mice studies全身检查使用高温超导谐振器体积老鼠先生的研究.pdf
- whole cell imprinting in sol-gel thin films for bacterial recognition in liquids macromolecular fingerprinting完整的细胞印迹溶胶-凝胶薄膜的细菌在液体高分子指纹识别.pdf
- whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia整个大脑辐射诱导在学习和记忆障碍对时间敏感的和可逆的系统性缺氧.pdf
- whole exome sequencing in a random sample of north american women with leiomyomas identifies med12 mutations in majority of uterine leiomyomas全外显子组测序在北美平滑肌瘤的女性的一个随机样本识别med12基因突变在多数子宫平滑肌瘤.pdf
- when time and numerosity interfere the longer the more, and the more the longer当时间和numerosity干涉越多,时间越长,越长越多.pdf
- whole farm net greenhouse gas abatement from establishing kikuyu-based perennial pastures in south-western australia整个农场净温室气体减排建立澳大利亚西南部kikuyu-based常年牧场.pdf
- whole genome duplication affects evolvability of flowering time in an autotetraploid plant全基因组重复影响可发展性的同源四倍体植物的开花时间.pdf
- whole genome deep sequencing of hiv-1 reveals the impact of early minor variants upon immune recognition during acute infection全基因组测序深度的hiv - 1揭示了早期轻微变异的影响在急性感染在免疫识别.pdf
- zearalenone and reproductive function in farm animals玉米烯酮和生殖功能的农场动物.pdf
- zebrafish arl6ip1 is required for neural crest development during embryogenesis斑马鱼arl6ip1在胚胎神经嵴的发展需要.pdf
- zebrafish agr2 is required for terminal differentiation of intestinal goblet cells斑马鱼agr2需要终端分化的肠道杯状细胞.pdf
- zeb2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in gliomazeb2介导多种通路调节细胞增殖、迁移,侵略,并在神经胶质瘤细胞凋亡.pdf
- zea mays irs1563 a comprehensive genome-scale metabolic reconstruction of maize metabolism玉蜀黍irs1563公司综合代谢重建玉米新陈代谢.pdf
- zeb1 regulates the latent-lytic switch in infection by epstein-barr viruszeb1调节latent-lytic开关在巴尔病毒感染.pdf
- zebrafish as a model system to study the physiological function of telomeric protein tpp1斑马鱼作为模型系统研究端粒的蛋白质tpp1的生理功能.pdf
- zebrafish endzone regulates neural crest-derived chromatophore differentiation and morphology斑马鱼开始调节神经嵴色素细胞分化和形态.pdf
- zebrafish cyclin-dependent protein kinase–like 1 (zcdkl1) identification and functional characterization斑马鱼细胞周期蛋白依赖性蛋白kinase-like 1(zcdkl1)识别和功能描述.pdf
- zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides斑马鱼化学筛选显示心脏苷多巴胺能神经元生存的障碍.pdf
文档评论（0）