有哪些信誉好的足球投注网站antimicrobial photodynamic therapy study of bacterial recovery viability and potential development of resistance after treatment抗菌光动力治疗研究细菌复苏的可行性和潜在的治疗后发展的阻力.pdfVIP
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antimicrobial photodynamic therapy study of bacterial recovery viability and potential development of resistance after treatment抗菌光动力治疗研究细菌复苏的可行性和潜在的治疗后发展的阻力
Mar. Drugs 2010, 8, 91-105; doi:10.3390/md8010091
OPEN ACCESS
Marine Drugs
ISSN 1660-3397
/journal/marinedrugs
Article
Antimicrobial Photodynamic Therapy: Study of Bacterial
Recovery Viability and Potential Development of Resistance
after Treatment
Anabela Tavares 1, Carla M. B. Carvalho 2, Maria A. Faustino 2, Maria G. P. M. S. Neves 2,*,
João P. C. Tomé 2, Augusto C. Tomé 2, José A. S. Cavaleiro 2, Ângela Cunha 1, Newton C. M.
Gomes 1, Eliana Alves 1 and Adelaide Almeida 1,*
1 CESAM and Department of Biology, University of Aveiro, Campus Universitário de Santiago,
3810-193 Aveiro, Portugal; E-Mails: anabelatavares@ua.pt (A.T.); acunha@ua.pt (A.C.);
gomesncm@ua.pt (N.C.M.G.); elianaalves@ua.pt (E.A.)
2 QOPNA and Department of Chemistry, University of Aveiro, Campus Universitário de Santiago,
3810-193 Aveiro, Portugal; E-Mails: ccarvalho@ua.pt (C.M.B.C.); faustino@ua.pt (M.A.F.);
jtome@ua.pt (J.P.C.T.); actome@ua.pt (A .C.T.); jcavaleiro@dq.ua.pt (J.A.S.C.)
* Authors to whom correspondence should be addressed; E-Mails: aalmeida@ua.pt (A.A.);
gneves@ua.pt (M.G.P.M.S.N.); Tel.: +351 234 370784; +351 234 370713.
Received: 29 December 2009; in revised form: 6 January 2010 / Accepted: 19 January 2010 /
Published: 20 January 2010
Abstract: Antimicrobial photodynamic therapy (aPDT) has emerged in the clinical field as
a potential alternative to antibiotics to treat microbial infections. No cases of microbial
viability recovery or any resistance mechanisms against it are yet known. 5,10,15-tris(1-
Methylpyridinium-4-yl)-20-(pe
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