有哪些信誉好的足球投注网站anthracenedione derivatives as anticancer agents isolated from secondary metabolites of the mangrove endophytic fungianthracenedione衍生品作为抗癌剂与红树林内生真菌的次生代谢产物.pdfVIP
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Mar. Drugs 2010, 8, 1469-1481; doi:10.3390/md8041469
OPEN ACCESS
Marine Drugs
ISSN 1660-3397
/journal/marinedrugs
Article
Anthracenedione Derivatives as Anticancer Agents Isolated
from Secondary Metabolites of the Mangrove Endophytic Fungi
1 1 1 1 1
Jian-ye Zhang , Li-yang Tao , Yong-ju Liang , Li-ming Chen , Yan-jun Mi ,
Li-sheng Zheng 1, Fang Wang 1, Zhi-gang She 2,*, Yong-cheng Lin 2, Kenneth Kin Wah To 3 and
Li-wu Fu 1,*
1 State Key Laboratory for Oncology in South China, Cancer Center, Sun Yat-Sen University,
Guangzhou, 510060, China; E-Mails: jianyez2003@ (J.Z.); sohutly@163.com (L.T.);
liangyju@ (Y.L.); chlm78@ (L.C.); myjgj_77@163.com (Y.M.);
lesley860221@163.com (L.Z.); wangfang0203@163.com (F.W.)
2 School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, 510275,
China
3 School of Pharmacy, The Chinese University of Hong Kong, Hong Kong, China;
E-Mail: kennethto@.hk (K.K.W.T.)
* Authors to whom correspondence should be addressed; E-Mails: Fulw@ (L.F.);
cesshzhg@ (Z.S.); Tel.: +86-20 Fax: +86-20
Received: 12 March 2010; in revised form: 1 April 2010 / Accepted: 21 April 2010 /
Published: 23 April 2010
Abstract: In this article, we report anticancer activity of 14 anthracenedione derivatives
separated from the secondary metabolites of the mangrove endophytic fungi Halorosellinia
sp. (No. 1403) and Guignardia sp. (No. 4382). Some of them inhibited potently the growth
of KB and KBv200 cells,
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