anatomical connectivity influences both intra- and inter-brain synchronizations解剖连接内部和间脑同步的影响.pdfVIP

Anatomical Connectivity Influences both Intra- and Inter- Brain Synchronizations 1,2,3,4 1,2,3,4 5 1,2,3,4 Guillaume Dumas *, Mario Chavez , Jacqueline Nadel , Jacques Martinerie ´ ´ ` 1 Universite Pierre et Marie Curie-Paris 6, Centre de Recherche de l’Institut du Cerveau et de la Moelle epiniere, UMR-S975, Paris, France, 2 Inserm, U975, Paris, France, ¨ ´ ` ´ 3 CNRS, UMR 7225, Paris, France, 4 ICM – Institut du Cerveau et de la Moelle epiniere, Paris, France, 5 Centre emotion, CNRS, USR 3246, Paris, France Abstract Recent development in diffusion spectrum brain imaging combined to functional simulation has the potential to further our understanding of how structure and dynamics are intertwined in the human brain. At the intra-individual scale, neurocomputational models have already started to uncover how the human connectome constrains the coordination of brain activity across distributed brain regions. In parallel, at the inter-individual scale, nascent social neuroscience provides a new dynamical vista of the coupling between two embodied cognitive agents. Using EEG hyperscanning to record simultaneously the brain activities of subjects during their ongoing interaction, we have previously demonstrated that behavioral synchrony correlates with the emergence of inter-brain synchronization. However, the functional meaning of such synchronization remains to be specified. Here, we use a biophysical model t