abnormally low and high ankle-brachial indices are independently associated with increased left ventricular mass index in chronic kidney disease异常低和高踝肱指数是独立与左心室质量指数增加有关慢性肾脏疾病.pdfVIP
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abnormally low and high ankle-brachial indices are independently associated with increased left ventricular mass index in chronic kidney disease异常低和高踝肱指数是独立与左心室质量指数增加有关慢性肾脏疾病
Abnormally Low and High Ankle-Brachial Indices Are
Independently Associated with Increased Left
Ventricular Mass Index in Chronic Kidney Disease
1,3,4 1,4 1 1 1 2,3
Ho-Ming Su , Tsung-Hsien Lin , Po-Chao Hsu , Chun-Yuan Chu , Wen-Hsien Lee , Szu-Chia Chen *,
Chee-Siong Lee1,4, Wen-Chol Voon1,4, Wen-Ter Lai1,4, Sheng-Hsiung Sheu1,4
1 Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, 2 Division of
Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, 3 Department of Internal
Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, 4 Faculty of Mecicine, College of Medicine, Kaohsiung Medical
University, Kaohsiung, Taiwan
Abstract
Abnormally low and high ankle-brachial indices (ABIs) are associated with high cardiovascular morbidity and mortality
in patients with chronic kidney disease (CKD), but the mechanisms responsible for the association are not fully known.
This study is designed to assess whether there is a significant correlation between abnormal ABI and echocariographic
parameters in patients with CKD stages 3–5. A total of 684 pre-dialysis CKD patients were included in the study. The ABI
was measured using an ABI-form device. Patients were classified into ABI ,0.9, $0.9 to ,1.3, and $1.3. Clinical and
echocariographic parameters were compared and analyzed. Compared with patients with ABI of $0.9 to ,1.3, the
values of left ventricular mass index (LVMI) were higher in patients with ABI ,0.9 and ABI $1.3 (P#0.004).
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