abo blood group system and gastric cancer a case-control study and meta-analysisabo血型系统和胃癌病例对照研究和荟萃分析.pdfVIP

Int. J. Mol. Sci. 2012, 13, 13308-13321; doi:10.3390/ijms131013308 OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article ABO Blood Group System and Gastric Cancer: A Case-Control Study and Meta-Analysis Zhiwei Wang †, Lei Liu †, Jun Ji, Jianian Zhang, Min Yan, Jun Zhang, Bingya Liu, Zhenggang Zhu and Yingyan Yu * Shanghai Key Laboratory of Gastric Neoplasms, Department of Surgery, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; E-Mails: surgerywangzw@ (Z.W.); surgeryliul@ (L.L.); surgeryjij@ (J.J.); surgeryzhangjanian@ (J.Z.); surgeryyanm@ (M.Y.); surgeryzhangjun@ (J.Z.); surgeryliuby@ (B.L.); surgeryzhu@ (Z.Z.) † These authors contributed equally to this work. * Author to whom correspondence should be addressed; E-Mail: yingyan3y@; Tel.: +86-21 Fax: +86-21 Received: 24 July 2012; in revised form: 3 September 2012 / Accepted: 8 October 2012 / Published: 17 October 2012 Abstract: This study focuses on the association between the ABO blood group system and the risk of gastric cancer or Helicobacter pylori infection. The data for the ABO blood group was collected from 1045 cases of gastric cancer, whereby the patient underwent a gastrectomy in Ruijin Hospital, Shanghai. The information on the ABO blood group from 53,026 healthy blood donors was enrolled as control. We searched the Pubmed database on the relat