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a virtual look at epstein–barr virus infection biological interpretations虚拟看巴尔病毒感染生物解释
A Virtual Look at Epstein–Barr Virus Infection:
Biological Interpretations
1,2[ 1,3[ 1,3,4 3 1
Karen A. Duca , Michael Shapiro , Edgar Delgado-Eckert , Vey Hadinoto , Abdul S. Jarrah ,
Reinhard Laubenbacher1 1 5 1,6 3*
, Kichol Lee , Katherine Luzuriaga , Nicholas F. Polys , David A. Thorley-Lawson
1 Virginia Bioinformatics Institute, Virginia Polytechnic and State University, Blacksburg, Virginia, United States of America, 2 Department of Biochemistry and Biotechnology,
Kwame Nkrumah University of Science and Technology, Kumasi, Ghanna, West Africa, 3 Department of Pathology, Tufts University School of Medicine, Boston,
¨ ¨ ¨
Massachusetts, United States of America, 4 Zentrum Mathematik der Technischen Universitat, Munchen, Garching bei Munchen, Germany, 5 Pediatrics and Molecular
Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, 6 Research and Cluster Computing, Virginia Tech Information
Technology, Virginia Polytechnic and State University, Blacksburg, Virginia, United States of America
The possibility of using computer simulation and mathematical modeling to gain insight into biological and other
complex systems is receiving increased attention. However, it is as yet unclear to what extent these techniques will
provide useful biological insights or even what the best approach is. Epstein–Barr virus (EBV) provides a good
candidate to address these
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