有哪些信誉好的足球投注网站a viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing一个病毒的发现方法为临床活检样本利用大规模并行下一代测序.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
a viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing一个病毒的发现方法为临床活检样本利用大规模并行下一代测序
A Viral Discovery Methodology for Clinical Biopsy
Samples Utilising Massively Parallel Next Generation
Sequencing
1 1 1 1 1 2
Gordon M. Daly , Nick Bexfield , Judith Heaney , Sam Stubbs , Antonia P. Mayer , Anne Palser , Paul
2 3 3 1 4 5
Kellam , Nizar Drou , Mario Caccamo , Laurence Tiley , Graeme J. M. Alexander , William Bernal ,
Jonathan L. Heeney1*
1 Department of Veterinary Medicine, The University of Cambridge, Cambridge, United Kingdom, 2 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus,
Hinxton, Cambridge, United Kingdom, 3 The Genome Analysis Centre, Norwich Research Park, Norwich, United Kingdom, 4 Department of Hepatology, Addenbrookes
Hospital, Cambridge University Hospitals National Health Services Foundation Trust, Cambridge, United Kingdom, 5 Institute of Liver Studies, King’s College London
School of Medicine, King’s College Hospital, Denmark Hill, London, United Kingdom
Abstract
Here we describe a virus discovery protocol for a range of different virus genera, that can be applied to biopsy-sized tissue
samples. Our viral enrichment procedure, validated using canine and human liver samples, significantly improves viral read
copy number and increases the length of viral contigs that can be generated by de novo assembly. This in turn enables the
Illumina next generation sequencing (NGS) platform to be used as an effective tool for viral discovery from tissue samples.
Citation: Daly GM, Bexfield N, Heaney J, Stubbs S, Mayer AP, et al. (2011) A Viral Discovery Methodology for Clinical Biopsy Samples Utilising Massively Parallel
Next Generation Sequencing. PLoS ONE 6(12): e28879. doi:10.1371/
您可能关注的文档
- a sexual shift induced by silencing of a single insulin-like gene in crayfish ovarian upregulation and testicular degeneration性转变一个胰岛素样基因沉默的诱导下,小龙虾卵巢upregulation和睾丸退化.pdf
- a set of novel microsatellite markers developed for luculia yunnanensis (rubiaceae), an endangered plant endemic to yunnan, china一套新颖的微卫星标记为luculia开发云南裂(茜草科),云南特有的濒危植物,中国.pdf
- a sex-ratio meiotic drive system in drosophila simulans. ii an x-linked distorter性别比例在果蝇simulans减数分裂驱动系统。.pdf
- a sex-specific metabolite identified in a marine invertebrate utilizing phosphorus-31 nuclear magnetic resonance海洋无脊椎动物的性别代谢物鉴定利用phosphorus-31核磁共振.pdf
- a short–time scale colloidal system reveals early bacterial adhesion dynamics短期范围内胶体系统揭示了早期细菌粘附动力学.pdf
- a sex-ratio meiotic drive system in drosophila simulans. i an autosomal suppressor性别比例在果蝇simulans减数分裂驱动系统。.pdf
- a signaling network for patterning of neuronal connectivity in the drosophila brain信号网络模式果蝇大脑的神经连接.pdf
- a signaling protease required for melanization in drosophila affects resistance and tolerance of infections果蝇的黑化作用所需信号蛋白酶影响抵抗感染和宽容.pdf
- a shrouded wind turbine generating high output power with wind-lens technology与wind-lens笼罩风力涡轮机发电输出功率高技术.pdf
- a short review on cardiotonic steroids and their aminoguanidine analogues一个简短的回顾强心剂类固醇和氨基胍类似物.pdf
- a viral vectored prime-boost immunization regime targeting the malaria pfs25 antigen induces transmission-blocking activity病毒载体启动u2014提高免疫机制针对疟疾pfs25抗原诱导阻断传播活动.pdf
- a virtual reprise of the stanley milgram obedience experiments一个虚拟的重奏斯坦利u2022米尔格拉姆的服从试验.pdf
- a virtual look at epstein–barr virus infection biological interpretations虚拟看巴尔病毒感染生物解释.pdf
- a unique role for nonmuscle myosin heavy chain iia in regulation of epithelial apical junctions一个独特的角色nonmuscle肌凝蛋白重链活动花絮调节上皮细胞顶端连接.pdf
- a virus-encoded cell–cell fusion machine dependent on surrogate adhesins一个病毒编码和信息融合机依赖代理丰富.pdf
- a viscoelastic deadly fluid in carnivorous pitcher plants食肉植物投手致命粘弹性流体.pdf
- a visual metaphor describing neural dynamics in schizophrenia视觉隐喻在精神分裂症神经动力学描述.pdf
- a virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trialvirosomal疟疾肽疫苗引发持久sporozoite-inhibitory抗体反应在第一阶段的临床试验.pdf
- a volumetric method for quantifying atherosclerosis in mice by using microct comparison to en face容积方法量化动脉粥样硬化小鼠通过microct相比在脸上.pdf
- a visual analytics approach for extracting spatio-temporal urban mobility information from mobile network traffic视觉分析方法提取时空城市流动信息从移动网络流量.pdf
文档评论（0）