肺心病血管扩张剂治疗右心衰竭的利与弊（Advantages and disadvantages of pulmonary heart disease vasodilator in the treatment of right heart failure）.docVIP

肺心病血管扩张剂治疗右心衰竭的利与弊（Advantages and disadvantages of pulmonary heart disease vasodilator in the treatment of right heart failure） Pulmonary heart disease: advantages and disadvantages of vasodilators in the treatment of right heart failure 2011-03-01 Liu Kunshen Gao Fengqi Pulmonary heart disease includes acute pulmonary heart disease (mainly caused by acute pulmonary embolism) and chronic pulmonary heart disease (COPD). COPD is characterized by right heart failure during acute exacerbation. The pathogenesis is caused by pulmonary infection, severe alveolar hypoxia, thickening of the pulmonary vascular wall, reduction of the pulmonary vascular bed area, and pulmonary hypertension, resulting in respiratory failure and right heart failure. Hypoxia is the major mechanism for the formation of pulmonary arterial hypertension. Active control of infection, mechanical ventilation can improve alveolar ventilation, correction of hypoxemia and hypercapnia, and the pulmonary arterial pressure and pulmonary vascular resistance decreased pulmonary blood flow rate (s/t) decreased 1, as the main means of respiratory failure and heart failure treatment for right; right ventricular failure. The vasodilator at present, there are different views on the application. 1 advantages and disadvantages of vasodilator use Vasodilators can reduce the preload and / or afterload of the heart, thereby reducing myocardial oxygen consumption, without decreasing or increasing cardiac output (CO). For some intractable right heart failure, especially acute pulmonary embolism caused by acute right heart failure, the use of thrombolytic agent thrombolysis and anticoagulation and vasodilator pulmonary vasodilator, should be the basic treatment, significant effect on acute right heart failure; but for COPD caused by right heart failure, blood vessel expansion agent treatment, and may make contraction or closed due to alveolar hypoxia related pulmonary artery and pulmonary capillary dilation or re opening, th