第三十一章肾上腺皮质激素类药（The thirty-first chapter adrenal cortex hormone medicine）.docVIP

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第三十一章肾上腺皮质激素类药（The thirty-first chapter adrenal cortex hormone medicine）.doc

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第三十一章肾上腺皮质激素类药（The thirty-first chapter adrenal cortex hormone medicine）

第三十一章肾上腺皮质激素类药（The thirty-first chapter adrenal cortex hormone medicine） Username, password, password, password back - youre not registered yet? Please register your account. The balance is RMB. The balance is insufficient. Please recharge it. Your account balance is $. The purchase will be deducted from your account and the cost will be $0. Station data unified decompression password: 100 content introduction, the thirty-first chapter of adrenal cortex hormone drugs To master the pharmacological action, mechanism, pharmacokinetics, clinical application, adverse reactions and contraindications of glucocorticoids. According to physiological functions, they are divided into three categories: mineralocorticoid, glucocorticoids and sex hormones. Among them, glucocorticoid is the most common clinical practice. Glucocorticoids [physiological function] Physiological dose mainly affects the three major substances and metabolism of water and salt. When the dose is too large or long-term use, it can lead to disorders of metabolism of various substances. The following are the main causes of adverse reactions and complications. 1, glucose metabolism: gluconeogenesis - liver and muscle glycogen synthesis; inhibition of uptake and oxidation of sugar, the cells with elevated blood sugar, diabetes (severe). 2, the metabolism of protein synthesis and decomposition: - - negative nitrogen balance, resulting in muscle atrophy, skin thinning, growth retardation, wound healing. 3, the metabolism of fat: fat synthesis, decomposition - induced ketoacidosis; fat redistribution of central obesity, moon face. 4, water and electrolyte metabolism: sodium retention, potassium excretion, water and sodium retention, hypokalemia, hypertension, increased calcium and phosphorus excretion, osteoporosis. 5, androgen like effects: acne, hirsutism and so on. [pharmacological effect] more than the physiological dose, in addition to affecting metabolism, there are still the following pharmacological effec