neglected tropical diseases in sub-saharan africa review of their prevalence, distribution, and disease burden被忽视的热带病撒哈拉以南非洲审查他们的患病率,分布和疾病负担.pdfVIP

Review Neglected Tropical Diseases in Sub-Saharan Africa: Review of Their Prevalence, Distribution, and Disease Burden Peter J. Hotez1,2*, Aruna Kamath1,2 1 Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University, Washington, D.C., United States of America, 2 Sabin Vaccine Institute, Washington, D.C., United States of America [3,6–8]. Because of their adverse effects on child development, Abstract: The neglected tropical diseases (NTDs) are the pregnancy outcome, and agricultural worker productivity [1,3,6,7,9– most common conditions affecting the poorest 500 17], the NTDs represent a major reason why the ‘‘bottom 500 million people living in sub-Saharan Africa (SSA), and million’’ people in SSA cannot escape poverty. Therefore, new and together produce a burden of disease that may be ongoing efforts to control and eliminate the NTDs represent key equivalent to up to one-half of SSA’s malaria disease elements for achieving Africa’s Millennium Development Goals burden and more than double that caused by tubercu- (MDGs) for sustainable poverty reduction, including the MDGs to losis. Approximately 85% of the NTD disease burden results from helminth infections. Hookworm infection eradicate poverty (MDG 1), promote education (MDG 2), reduce occurs in almost half of SSA’s poorest people, including child mortality (MDG 4), improve maternal health (MDG 5), and to