hypertension and obesity as cardiovascular risk factors among hiv seropositive patients in western kenya高血压和肥胖是心血管危险因素在艾滋病毒血清反应阳性的病人在肯尼亚西部.pdfVIP

Hypertension and Obesity as Cardiovascular Risk Factors among HIV Seropositive Patients in Western Kenya 1 2 3 3 4 Gerald S. Bloomfield *, Joseph W. Hogan , Alfred Keter , Edwin Sang , E. Jane Carter , Eric J. Velazquez1, Sylvester Kimaiyo3 1 Division of Cardiology and Duke Clinical Research Institute, Duke University, Durham, North Carolina, United States of America, 2 Department of Biostatistics, Brown University, Providence, Rhode Island, United States of America, 3 Department of Medicine, Moi University School of Medicine, Eldoret, Kenya, 4 Divisions of Infectious Diseases and Pulmonary Medicine, Alpert School of Medicine at Brown University, Providence, Rhode Island, United States of America Abstract Background: There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived from developed country settings. Herein, we describe the prevalence of hypertension and obesity in a large HIV treatment program in Kenya. Methods: We performed a retrospective analysis of the electronic medical records of a large HIV treatment program in Western Kenya between 2006 and 2009. We calculated the prevalence of hypertension and obesity among HIV+ adults as well as utilized multiple logistic regression analyses to examine the relationship between clinical characteristics, HIV-related characteristics, and hypertension. Results: Our final sample size was 12,194. The median systolic/diastolic blood pressures were similar for both sexes (male: 110/70 mmHg, female: 110/70 mmHg). The prevalence of hypertension among men and women were 11.2% and 7.4%, respectively. Eleven percent of men and 22.6% of women were o