有哪些信誉好的足球投注网站high expression of testes-specific protease 50 is associated with poor prognosis in colorectal carcinoma高50 testes-specific蛋白酶的表达与结直肠癌预后不良有关.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
high expression of testes-specific protease 50 is associated with poor prognosis in colorectal carcinoma高50 testes-specific蛋白酶的表达与结直肠癌预后不良有关
High Expression of Testes-Specific Protease 50 Is Associated with Poor Prognosis in Colorectal Carcinoma 1. 2. 3 3 1 Lei Zheng , Ganfeng Xie , Guangjie Duan , Xiaochu Yan , Qianwei Li * 1 Department of Nuclear Medicine, Southwest Hospital, Third Military Medical University, Chongqing, China, 2 Department of Oncology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing, China, 3 Department of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing, China Abstract Background: Testes-specific protease 50 (TSP50) is normally expressed in testes and abnormally expressed in breast cancer, but whether TSP50 is expressed in colorectal carcinoma (CRC) and its clinical significance is unclear. We aimed to detect TSP50 expression in CRC, correlate it with clinicopathological factors, and assess its potential diagnostic and prognostic value. Methodology/Principal Findings: TSP50 mRNAs and proteins were detected in 7 CRC cell lines and 8 CRC specimens via RT- PCR and Western blot analysis. Immunohistochemical analysis of TSP50, p53 and carcinoembryonic antigen (CEA) with tissue microarrays composed of 95 CRCs, 20 colorectal adenomas and 20 normal colorectal tissues were carried out and correlated with clinicopathological characteristics and disease-specific survival for CRC patients. There was no significant correlation between the expression levels of TSP50 and p53 (P = 0.751) or CEA (P = 0.663). Abundant expression of TSP50 protein was found in CRCs (68.4%) while it was poorly expressed in colorectal adenomas and normal tissues (P,0.0001). Thus, CRCs can be distinguished from them with high specificity (92.5%) and positive predictive value (PPV, 95.6%). The
您可能关注的文档
- going against the grain这违背了.pdf
- going beyond clustering in md trajectory analysis an application to villin headpiece folding超越在md轨迹聚类分析应用程序villin帽子折叠.pdf
- glycogen synthase kinase 3 beta (gsk3β) phosphorylates the rnaase iii enzyme drosha at s300 and s302糖原合成酶激酶3β(gsk3β)磷酸化核糖核酸酶iii酶drosha s300和s302.pdf
- going, going, gone is animal migration disappearing走,走,走了是动物迁移消失.pdf
- glycyrrhizin exerts antioxidative effects in h5n1 influenza a virus-infected cells and inhibits virus replication and pro-inflammatory gene expression甘草甜素发挥抗氧化作用在h5n1流感病毒感染细胞,抑制病毒复制和促炎症基因的表达.pdf
- good and bad in the hands of politicians spontaneous gestures during positive and negative speech好的和坏的政客手中的自发手势在积极和消极的言论.pdf
- golgi disruption and early embryonic lethality in mice lacking uso1高尔基体破坏和早期胚胎小鼠缺乏uso1杀伤力.pdf
- golden gate shuffling a one-pot dna shuffling method based on type iis restriction enzymes金门洗牌锅dna洗牌方法基于类型iis限制性内切酶.pdf
- good clinical laboratory practices improved proficiency testing performance at clinical trials centers in ghana and burkina faso良好的临床实验室实践提高了熟练测试性能在临床试验中心在加纳和布基纳法索.pdf
- good glycemic control is associated with better survival in diabetic patients on peritoneal dialysis a prospective observational study良好的血糖控制与更好的生存在糖尿病患者腹膜透析前瞻性观察性研究.pdf
- high burden of prevalent and recently acquired hiv among female sex workers and female hiv voluntary testing center clients in kigali, rwanda高负担和最近收购了艾滋病毒流行的女性性工作者和女性艾滋病自愿检测中心客户在基加利,卢旺达.pdf
- high cd8+ t cell activation marks a less differentiated hiv-1 specific cd8+ t cell response that is not altered by suppression of viral replication高cd8 + t细胞活化标志着少分化hiv - 1特定的cd8 + t细胞反应,不是被抑制病毒复制.pdf
- high fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance高脂肪食源性老鼠肌肉线粒体磷脂的变化不影响线粒体呼吸尽管胰岛素抵抗.pdf
- high fragmentation characterizes tumour-derived circulating dna高分段描述肿瘤提取循环dna.pdf
- high expression levels of total igf-1r and sensitivity of nsclc cells in vitro to an anti-igf-1r antibody (r1507)高表达水平的总igf-1r和敏感性的非小细胞肺癌细胞体外anti-igf-1r抗体(r1507).pdf
- high frequency of copy number variations and sequence variants at cyp21a2 locus implication for the genetic diagnosis of 21-hydroxylase deficiency高拷贝数变化的频率和序列变异cyp21a2轨迹隐含21-hydroxylase基因诊断的不足之处.pdf
- high diabetes prevalence among tuberculosis cases in kerala, india印度喀拉拉邦的结核病例中糖尿病患病率高.pdf
- high genetic diversity and different distributions of glycosyl hydrolase family 10 and 11 xylanases in the goat rumen较高的遗传多样性和不同分布的糖基水解酶家族在山羊瘤胃10和11木聚糖酶.pdf
- high genetic diversity despite the potential for stepping-stone colonizations in an invasive species of gecko on moorea, french polynesia较高的遗传多样性,尽管潜在的踏脚石殖民入侵物种的壁虎在莫雷阿岛,法属波利尼西亚.pdf
- high glucose-mediated oxidative stress impairs cell migration高glucose-mediated氧化应激损害细胞迁移.pdf
文档评论（0）