going against the grain这违背了.pdfVIP

Feature Going against the Grain Overturning the received wisdom of a field takes not just strong evidence, but a strong personality. For one reproductive biologist, only time will tell whether such challenges are worth the risks in today’s pressurized research climate. Kendall Powell he data that would change the course of Jonathan problems—for example, infertility treatments after cancer Tilly’s career and cause an uproar in the field of therapy or for aging women, and for ovarian failure, a Tovarian biology almost never saw the light of day. In condition related to menopause—may be based on false Tilly’s cell death lab, postdoctoral fellow Tomoko Kaneko had assumptions. twice repeated her experiments to kill off mouse egg cells, “Controversy is a very vital part of the scientific process,” but something was wrong because the egg cell numbers were says Roger Gosden, an ovarian expert at Weill Cornell still high after treatment with a chemotherapy drug. Kaneko Medical School in New York City. “It’s the critical nature consulted another postdoc in the lab, Josh Johnson, and of science which gives it its strength and authority.” together they tried to determine if she had made a technical Though critical of Tilly’s interpretations, Gosden admits mistake or perhaps switched her control and experimental that the question of regeneration is so important to the groups. field of reproductive biology that it should be investigated “All of us ‘knew’ that egg regeneration couldn’t be thoroughly. occurring,” says Johnson, referring to the long-held view This particular controversy makes a compelling case study that adult female mamma