有哪些信誉好的足球投注网站hf-epr, raman, uvvis light spectroscopic, and dft studies of the ribonucleotide reductase r2 tyrosyl radical from epstein-barr virushf-epr,拉曼、依照此光光谱和dft的研究从巴尔病毒核苷酸还原酶r2酪氨酰激进.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
hf-epr, raman, uvvis light spectroscopic, and dft studies of the ribonucleotide reductase r2 tyrosyl radical from epstein-barr virushf-epr,拉曼、依照此光光谱和dft的研究从巴尔病毒核苷酸还原酶r2酪氨酰激进
HF-EPR, Raman, UV/VIS Light Spectroscopic, and DFT Studies of the Ribonucleotide Reductase R2 Tyrosyl Radical from Epstein-Barr Virus 1 1 2¤ 1 3 Ane B. Tomter , Giorgio Zoppellaro , Florian Schmitzberger , Niels H. Andersen , Anne-Laure Barra , 2 ¨ 2 1 Henrik Engman , Par Nordlund , K. Kristoffer Andersson * 1 Department of Molecular Biosciences, University of Oslo, Oslo, Norway, 2 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden, ´ 3 Laboratoire National des Champs Magnetiques Intenses, LNCMI-G, UPR 3228, CNRS, Grenoble, France Abstract Epstein-Barr virus (EBV) belongs to the gamma subfamily of herpes viruses, among the most common pathogenic viruses in humans worldwide. The viral ribonucleotide reductase small subunit (RNR R2) is involved in the biosynthesis of nucleotides, the DNA precursors necessary for viral replication, and is an important drug target for EBV. RNR R2 generates a stable tyrosyl radical required for enzymatic turnover. Here, the electronic and magnetic properties of the tyrosyl radical in EBV R2 have been determined by X-band and high-field/high-frequency electron paramagnetic resonance (EPR) spectroscopy recorded at cryogenic temperatures. The radical exhibits an unusually low g1-tensor component at 2.0080, indicative of a positive charge in the vicinity of the radical. Consistent with these EPR results a relatively high C-O stretching frequency associated with the phenoxyl radical (at 1508 cm 21) is observed with resonance Raman spectroscopy. In contrast to mouse R2,
您可能关注的文档
- global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses全球转录组分析influenza-infected鼠肺显示先天和适应宿主免疫反应的动力学.pdf
- global trends and factors associated with the illegal killing of elephants a hierarchical bayesian analysis of carcass encounter data全球趋势和因素与非法猎杀大象尸体遇到的分层贝叶斯分析数据.pdf
- globalization and loss of plant knowledge challenging the paradigm全球化和损失的植物知识挑战模式.pdf
- global trophic position comparison of two dominant mesopelagic fish families (myctophidae, stomiidae) using amino acid nitrogen isotopic analyses全球营养状况的比较两个主要海洋中层的鱼家庭(灯笼鱼科,stomiidae)使用氨基酸氮同位素分析.pdf
- global versus local conservation focus of u.s. state agency endangered bird species lists全局与局部保护美国的国家机构的重点濒危鸟类列表.pdf
- glp-1 receptor activation inhibits vldl production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed apoe3-leiden miceglp-1受体激活抑制vldl生产和逆转肝脂肪变性肝脂肪生成减少high-fat-fed apoe3-leiden老鼠.pdf
- glp2-2g-xten a pharmaceutical protein with improved serum half-life and efficacy in a rat crohn’s disease modelglp2-2g-xten医药蛋白改善血清半衰期和有效性在一只老鼠克罗恩病模型.pdf
- glucagon like peptide-1-induced glucose metabolism in differentiated human muscle satellite cells is attenuated by hyperglycemia胰高糖素像peptide-1-induced葡萄糖代谢在人类肌肉卫星细胞分化是由高血糖减毒.pdf
- glucocorticoid effects on the programming of at1b angiotensin receptor gene methylation and expression in the rat糖皮质激素影响编程at1b血管紧张素受体基因甲基化和表达的老鼠.pdf
- glucocorticoid receptor-dependent gene regulatory networks糖皮质激素receptor-dependent基因调控网络.pdf
- heterozygous mutations of frem1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice的杂合突变frem1与风险增加有关的孤立metopic颅缝早闭在人类和老鼠.pdf
- hfr1 is crucial for transcriptome regulation in the cryptochrome 1-mediated early response to blue light in arabidopsis thalianahfr1至关重要的转录组监管隐花色素1-mediated早反应在拟南芥蓝灯.pdf
- heterogeneity in sdf-1 expression defines the vasculogenic potential of adult cardiac progenitor cells异质性在sdf-1表达式定义vasculogenic成人心脏祖细胞的潜力.pdf
- hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network等级分化的骨髓祖细胞转录因子网络编码.pdf
- hidden epistastic interactions can favour the evolution of sex and recombination隐藏epistastic交互可以支持的进化性和重组.pdf
- hierarchical processing of auditory objects in humans在人类听觉对象的分层处理.pdf
- hierarchical unilamellar vesicles of controlled compositional heterogeneity层次单膜囊泡的成分非均质性控制.pdf
- hierarchy measure for complex networks复杂网络层次结构的措施.pdf
- hif-1 and skn-1 coordinate the transcriptional response to hydrogen sulfide in caenorhabditis eleganshif-1 skn-1协调转录反应在秀丽隐杆线虫硫化氢.pdf
- hif-1 regulates iron homeostasis in caenorhabditis elegans by activation and inhibition of genes involved in iron uptake and storagehif-1调节体内铁稳态线虫基因的激活和抑制铁的吸收和存储.pdf
文档评论（0）