有哪些信誉好的足球投注网站hfr1 is crucial for transcriptome regulation in the cryptochrome 1-mediated early response to blue light in arabidopsis thalianahfr1至关重要的转录组监管隐花色素1-mediated早反应在拟南芥蓝灯.pdfVIP
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hfr1 is crucial for transcriptome regulation in the cryptochrome 1-mediated early response to blue light in arabidopsis thalianahfr1至关重要的转录组监管隐花色素1-mediated早反应在拟南芥蓝灯
HFR1 Is Crucial for Transcriptome Regulation in the Cryptochrome 1-Mediated Early Response to Blue Light in Arabidopsis thaliana 1.¤a 1.¤b 2 2 3 1¤c Xiao-Ning Zhang *, Yingjie Wu , John W. Tobias , Brian P. Brunk , Gerald F. Deitzer , Dongmei Liu 1 Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, 2 Center for Bioinformatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, 3 Department of Plant Science and Landscape Architecture, University of Maryland, College Park, Maryland, United States of America Abstract Cryptochromes are blue light photoreceptors involved in development and circadian clock regulation. They are found in both eukaryotes and prokaryotes as light sensors. Long Hypocotyl in Far-Red 1 (HFR1) has been identified as a positive regulator and a possible transcription factor in both blue and far-red light signaling in plants. However, the gene targets that are regulated by HFR1 in cryptochrome 1 (cry1)-mediated blue light signaling have not been globally addressed. We examined the transcriptome profiles in a cry1- and HFR1-dependent manner in response to 1 hour of blue light. Strikingly, more than 70% of the genes induced by blue light in an HFR1-dependent manner were dependent on cry1, and vice versa. High overrepresentation of W-boxes and OCS elements were found in these genes, indicating that this strong cry1 and HFR1 co-regulation on gene expression is possibly through these two cis-elements. We also found that cry1 was required for maintaining the HFR1 protein level in blue light, and that the HFR1 protein level is strongly correlated with the global gene
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