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head circumference of infants born to mothers with different educational levels; the generation r study头围的不同教育水平的母亲产下的婴儿;
Head Circumference of Infants Born to Mothers with Different Educational Levels; The Generation R Study 1,2 2 3 ¨ 3 Selma H. Bouthoorn , Frank J. van Lenthe , Anita C. S. Hokken-Koelega , Henriette A. Moll , 4,5 1,4 2 1,3,4 2 Henning Tiemeier , Albert Hofman , Johan P. Mackenbach , Vincent W. V. Jaddoe , Hein Raat * 1The Generation R Study Group, Erasmus Medical Centre, Rotterdam, the Netherlands, 2 Department of Public Health, Erasmus Medical Centre, Rotterdam, the Netherlands, 3 Department of Pediatrics, Erasmus Medical Centre, Rotterdam, the Netherlands, 4 Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands, 5 Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, the Netherlands Abstract Objective: Head circumference (HC) reflect growth and development of the brain in early childhood. It is unknown whether socioeconomic differences in HC are present in early childhood. Therefore, we investigated the association between socioeconomic position (SEP) and HC in early childhood, and potential underlying factors. Methods: The study focused on Dutch children born between April 2002 and January 2006 who participated in The Generation R Study, a population-based prospective cohort study in Rotterdam, the Netherlands. Maternal educational level was used as indicator of SEP. HC measures were concentrated around 1, 3, 6 and 11 months. Associations and explanatory factors were investigated using linear regression analysis, adjusted for potential mediators. R
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