global distribution of outbreaks of water-associated infectious diseases全球传染病而暴发的分布.pdfVIP

Global Distribution of Outbreaks of Water-Associated Infectious Diseases 1,2 3 4 1 4 1 Kun Yang , Jeffrey LeJeune , Doug Alsdorf , Bo Lu , C. K. Shum , Song Liang * 1 College of Public Health, The Ohio State University, Columbus, Ohio, United States of America, 2 Department of Schistosomiasis, Jiangsu Institute of Parasitic Diseases, Wuxi, People’s Republic of China, 3 Ohio Agricultural Research and Development Center, Wooster, Ohio, United States of America, 4 School of Earth Sciences, The Ohio State University, Columbus, Ohio, United States of America Abstract Background: Water plays an important role in the transmission of many infectious diseases, which pose a great burden on global public health. However, the global distribution of these water-associated infectious diseases and underlying factors remain largely unexplored. Methods and Findings: Based on the Global Infectious Disease and Epidemiology Network (GIDEON), a global database including water-associated pathogens and diseases was developed. In this study, reported outbreak events associated with corresponding water-associated infectious diseases from 1991 to 2008 were extracted from the database. The location of each reported outbreak event was identified and geocoded into a GIS database. Also collected in the GIS database included geo-referenced socio-environmental information including population density (2000), annual accumulated temperature, surface water area, and average annual precipitation. Poisson models with Bayesian inference were developed to explore the association between these socio-environmental factors and distribution of the reported outbreak events. Based on model predictions a global relative risk map was generated. A total of 1,428 reported outbreak event