global gene expression profiling of human pleural mesotheliomas identification of matrix metalloproteinase 14 (mmp-14) as potential tumour target全球人类的基因表达图谱胸膜间皮瘤能够识别基质金属蛋白酶14(mmp-14)作为一个潜在的肿瘤的目标.pdfVIP

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global gene expression profiling of human pleural mesotheliomas identification of matrix metalloproteinase 14 (mmp-14) as potential tumour target全球人类的基因表达图谱胸膜间皮瘤能够识别基质金属蛋白酶14(mmp-14)作为一个潜在的肿瘤的目标.pdf

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global gene expression profiling of human pleural mesotheliomas identification of matrix metalloproteinase 14 (mmp-14) as potential tumour target全球人类的基因表达图谱胸膜间皮瘤能够识别基质金属蛋白酶14(mmp-14)作为一个潜在的肿瘤的目标

Global Gene Expression Profiling Of Human Pleural Mesotheliomas: Identification of Matrix Metalloproteinase 14 (MMP-14) as Potential Tumour Target 1 2 3 4 5 Stefania Crispi *, Raffaele A. Calogero , Mario Santini , Pasquale Mellone , Bruno Vincenzi , Gennaro 6 3 7 7 7 8 Citro , Giovanni Vicidomini , Silvia Fasano , Rosaria Meccariello , Gilda Cobellis , Simona Menegozzo , 7 9 4 7,8 Riccardo Pierantoni , Francesco Facciolo , Alfonso Baldi , Massimo Menegozzo 1 Gene Expression Core - Human Molecular Genetics Laboratory, Institute of Genetics and Biophysics, Naples, Italy, 2 Bioinformatics and Genomics Unit, Department of Clinical and Biological Science, University of Turin, Turin, Italy, 3 Department of Thoracic Surgery, Second University of Naples, Naples, Italy, 4 Department of Biochemistry, Sect. Pathology, Second University of Naples, Naples, Italy, 5 Campus BioMedico University, Section of Oncology, Rome, Italy, 6 SAFU Department, CRS, Regina Elena Cancer Institute, Rome, Italy, 7 Department of Experimental Medicine, Second University of Naples, Naples, Italy, 8 Campania Regional Operating Center (COR) of the National Mesothelioma Registry (ReNaM) - Department of Experimental Medicine, Second University of Naples, Naples, Italy, 9 Department of Thoracic Surgery, Regina Elena Cancer Institute, Rome, Italy Abstract Background: The goal of our study was to molecularly dissect mesothelioma tumour pathways by mean of microarray technologies in order to identify new tumour biomarkers that could b