有哪些信誉好的足球投注网站a human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen一个人形senescence-associated分泌表型是守恒的老鼠细胞依赖于生理上的氧气.pdfVIP
- 1、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
a human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen一个人形senescence-associated分泌表型是守恒的老鼠细胞依赖于生理上的氧气
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen ´ 1,2¤a 1,2. 1,2.¤b 1¤c Jean-Philippe Coppe , Christopher K. Patil , Francis Rodier , Ana Krtolica , Christian M. ´ 3 1¤d 4¤e 4 1,2,5 Beausejour , Simona Parrinello , J. Graeme Hodgson , Koei Chin , Pierre-Yves Desprez , Judith Campisi1,2* 1 Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America, 2 Buck Institute for Age Research, Novato, California, United ´ ´ ´ ´ ´ States of America, 3 Centre de Recherche du CHU Ste-Justine et Departement de Pharmacologie, Universite de Montreal, Montreal, Quebec, Canada, 4 Department of Laboratory Medicine, Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America, 5 California Pacific Medical Center Research Institute, San Francisco, California, United States of America Abstract Cellular senescence irreversibly arrests cell proliferation in response to oncogenic stimuli. Human cells develop a senescence-associated secretory phenotype (SASP), which increases the secretion of cytokines and other factors that alter the behavior of neighboring cells. We show here that ‘‘senescent’’ mouse fibroblasts, which arrested growth after repeated passage under standard culture conditions (20% oxygen),
您可能关注的文档
- a bow-tie genetic architecture for morphogenesis suggested by a genome-wide rnai screen in caenorhabditis elegans蝴蝶结的遗传体系结构形态发生建议秀丽隐杆线虫的基因组rnai屏幕.pdf
- a broad set of different llama antibodies specific for a 16 kda heat shock protein of mycobacterium tuberculosis一系列的不同的骆驼抗体特定16 kda热休克蛋白的结核分枝杆菌.pdf
- a c. elegans model for mitochondrial fatty acid synthase ii the longevity-associated gene w09h1.5mecr-1 encodes a 2-trans-enoyl-thioester reductase秀丽隐杆线虫模型线粒体脂肪酸合酶ii与长寿相关的基因w09h1.5mecr-1编码2-trans-enoyl-thioester还原酶.pdf
- a broad requirement for tls polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during c. elegans embryogenesistls聚合酶的广泛要求ηκ,sumoylation和核孔蛋白相互作用,在秀丽隐杆线虫胚胎发生病变绕过.pdf
- a broken trust lessons from the vaccine–autism wars打破信任教训自闭症的战争.pdf
- a burst-based “hebbian” learning rule at retinogeniculate synapses links retinal waves to activity-dependent refinementburst-basedu201chebbianu201d学习规则在视网膜电波活动依赖性细化retinogeniculate突触联系.pdf
- a c1q domain containing protein from scallop chlamys farreri serving as pattern recognition receptor with heat-aggregated igg binding activityc1q域包含蛋白质扇贝斗篷farreri作为模式识别受体与heat-aggregated免疫球蛋白结合的活动.pdf
- a brain-computer interface based attention training program for treating attention deficit hyperactivity disorder基于脑机接口的注意力训练计划治疗注意缺陷多动障碍.pdf
- a buoyancy-based screen of drosophila larvae for fat-storage mutants reveals a role for sir2 in coupling fat storage to nutrient availabilitybuoyancy-based屏幕积聚脂肪突变体果蝇幼虫的揭示了一个角色在耦合sir2脂肪储存营养的可用性.pdf
- a canadian perspective加拿大的角度来看.pdf
- a java program for lre-based real-time qpcr that enables large-scale absolute quantificationjava程序lre-based实时qpcr,使大规模的绝对量化.pdf
- a key role for the endothelium in nod1 mediated vascular inflammation comparison to tlr4 responses一个关键的角色在nod1介导血管内皮炎症比较tlr4的反应.pdf
- a key role of dendritic cells in probiotic functionality在益生菌树突状细胞功能的一个关键的角色.pdf
- a kernel for open source drug discovery in tropical diseases一个内核的开源药物发现的热带疾病.pdf
- a j-like protein influences fatty acid composition of chloroplast lipids in arabidopsisj-like蛋白质在拟南芥叶绿体脂质脂肪酸组成的影响.pdf
- a key role for chd1 in histone h3 dynamics at the 3′ ends of long genes in yeast一个关键的角色在组蛋白h3 chd1动力学3u2032末端的基因在酵母.pdf
- a key tumor suppressor protein ensures proper chromosome segregation during cell division关键的肿瘤抑制蛋白确保适当的细胞分裂时染色体的分离.pdf
- a kinase-independent role for the rad3atr-rad26atrip complex in recruitment of tel1atm to telomeres in fission yeastrad3atr-rad26atrip kinase-independent角色复杂的招聘tel1atm裂殖酵母端粒.pdf
- a kinetic model of dopamine- and calcium-dependent striatal synaptic plasticity多巴胺的动力学模型和calcium-dependent纹状体突触可塑性.pdf
- a kinetic model of trp-cage folding from multiple biased molecular dynamics simulationstrp-cage折叠的动力学模型从多个有偏见的分子动力学模拟.pdf
文档评论（0）