30T磁共振在直肠癌术前评估中序列的优选.docVIP

3.0T磁共振在直肠癌术前评估中扫描序列的优选 研究生：何鑫 导师：刘艳 副教授/主任医师 摘 要 目的：探讨3.0T磁共振在直肠癌术前评估中扫描序列的最优选择。方法：根据指定的扫描序列对已确诊的61例直肠癌患者进行术前T、N分期并测量肿瘤的纵向浸润范围，将MRI诊断结果与术后病理结果作对照。结果：T2WI-TRA(the T2 weighted image- Transverse，T2WI-TRA)联合DWI序列、T2WI-TRA序列、T1WI-TRA+DCE(T1 weighted imgae-Transverse Dynamic contrast-enhanced image,T1WI-TRA+DCE)序列在T分期总准确率分别为90.16%、78.69%、83.61%。薄层T2WI-COR联合DWI序列、薄层T2WI-COR序列、T1WI-CE序列的N分期总准确率分别为81.97%、73.78%、72.13%。T2WI-SAG联合DWI序列测量肿瘤的纵向浸润范围与病理结果采用配对样本t检验分析，两者差异无统计学意义（P0.05）。结论：3.0T磁共振在直肠癌术前评估中的最优扫描序列是：T2WI-TRA序列、薄层T2WI-COR序列、T2WI-SAG序列及DWI（b=0和1000s/mm2）序列。 关键词: 直肠癌；术前分期；磁共振；扫描序列 The priority selection of scanning sequence of preoperative assessment of rectal cancer of 3.0T MR Postgraduate:He Xin Supervisor:Ass.Prof. Liu yan Abstract Objective:To discuss the priority selection of scanning sequence of preoperative assessment of rectal cancer of 3.0T MR. Methods:61 patients with rectal cancer underwent preoperative T, N staging and measure vertical infiltration range of tumor according to specified scanning sequence, contrast the MRI findings and postoperative pathological findings.Results:The total accuracy of T staging of T2WI-TRA combined Diffusion weighted image DWI sequence,T2WI-TRA sequence,T1 weighted-Dynamic contrast-enhanced image T1WI-DCE sequence was respectively 90.16%,78.69% and 83.61%.The total accuracy of of N staging of T2 weighted image-Coronal T2WI-COR thin layer combined DWI sequence,T2WI-COR thin layer sequence,T1 weighted -contrast-enhanced image T1WI-CE sequence was respectively 81.97%,73.78% and 72.13%.Using paired samples T test to analyse the results have no statistical difference between T2WI-TRA combined DWI sequence and pathological (P0.05).Conclusion:The priority selection of scanning sequence of preoperative assessment of rectal cancer of 3.0T MR is T2WI-TRA, T2WI-COR thin layer, T2 weighted image-Sagittal T2WI-SAG and DWI（b=0 and 1000 s / mm2）sequence.Key words: Rectal cancer;Preoperative staging;Magnetic resonance;Scanning sequence