CT及MRI图像融合对脑转移瘤三维适形放疗靶区影响.docVIP

CT及MRI图像融合对脑转移瘤三维适形放疗靶区影响[摘要] 目的 研究CT与MRI图像融合的脑转移瘤靶区与CT图像靶区的不同，提高三维适形放疗靶区勾画的准确性。 方法 同期采集25例脑转移瘤患者的CT和MRI图像，传送至图像处理工作站融合成CT/MRI图像，分别在CT及CT/MRI融合图像勾画41组GTV，比较两种图像勾画的GTV的差别。 结果25例患者共41组靶区的GTVCT 为（31.75±9.93）cm3，GTVCT/MRI为（28.92±8.25）cm3 。41个对照组中，GTVCT GTVCT/MRI为23个。 结论 采用CT/MRI融合后图像勾画的脑转移瘤靶区精确度提高，更适合于三维立体适形放疗。 [关键词] CT/MRI图像融合；脑转移瘤；靶区勾画 [中图分类号] R739.41 [文献标识码] A [文章编号] 1673-7210（2012）07（b）-0075-02 The influence of target volume by CT/MRI image fusion on brain metastasis′s three-dimensional conformal radiotherapy CHEN Suwei YUAN Feng LIN Zhiren WANG Weifeng Department of Radiation and Medical Oncology, the People’s Hospital of Haikou City, Hainan Province, Haikou 570000, China [Abstract] Objective To improve the accuracy of delineating three-dimensional conformal radiotherapy target volume by comparing the difference between computed tomography(CT)/magnetic resonance imaging (MRI) image fusion on brain metastasis area and CT′s target area. Methods CT′s images and MRI′s images collected from 25 cases with brain metastasis in the same period were transmitted to image processing workstation and fused into CT/MRI images, and then 41 pairs of gross tumor volume (GTV) were delineated in CT and CT/MRI, and finally difference was compared between the two group. Results The value of GTVCT in 41 pairs from 25 cases was (31.75±9.93) cm3 and in GTVCT/MRI was (28.92±8.25) cm3. Among 41 control groups, the number of the accuracy of GTVCT lower than that of GTVCT/MRI was 18, GTCCT higher than that of GTVCT/MRI was 23. Conclusion The improving accuracy of brain metastasis′s target volume sketched by CT/MRI image fusion is more suitable for three-dimensional conformal radiotherapy. [Key words] CT/MRI image fusion; Brain metastasis; Target volume delineation 在颅内肿瘤中，转移瘤所占比例为10%～15%，常伴有多发。对不能手术或手术不全的患者，放疗是主要的治疗方法。颅内肿瘤的三维适形放疗（three-dimensional conformal radiotherapy，3D-CRT）中，靶区勾画准确是精确治疗的关键环节，靶区显像的分辨率相当重要。核磁共振成像（magnatic resonance image，MRI）对颅内肿瘤的显像有明显优势，但图像边缘存在几何变形的问题，定位的