麻醉对兔膀胱肌电检测影响的实验研究.pdfVIP

14OO 重庆医学2008年7月第37卷第13期 · 论 著 · 麻醉对兔膀胱肌电检测影响的实验研究 刘朝东，张 明▲，龚 旭 (重庆医科大学附属第一医院泌尿外科 400016) 摘 要：目的 探讨麻醉对兔膀胱肌电检测影响，更进一步了解膀胱肌电检测的影响因素。方法 将免随机分为麻醉组和非 麻醉组(每组1O只)，利用体表电极、膀胱直接电极、压力传感器，分别同步记录兔在贮尿和排尿期的体表膀胱肌电、体内膀胱平滑 肌电和膀胱内压力信号，通过计算机进行数据处理，并对它们进行相关性分析及差异比较。结果 贮尿期，两组动物均未记录到 明显的电信号；排尿期，麻醉组：体表肌电的平均振幅和频率与从膀胱壁记录到的均有明显相关(r一0．937 1和r一0．993 0，P 0．01)，前者比后者的振幅明显下降(t=44．41，P0．01)，频率之间的差异则无统计学意义(t一一0．83，P0．05)；非麻醉组：体表 肌电的平均振幅和频率与从膀胱壁记录到的均有明显相关(r一0．974 1和r一0．993 0，P0．01)，振幅及频率之间的差异均无统 计学意义(P0．05)。但麻醉和非麻醉组体表肌电之间的振幅存在明显差异(t一41．23，P0．01)。结论 清醒及麻醉状态下的 体表膀胱肌电均反映了膀胱壁平滑肌的电活动及功能活动，但清醒状态下体表肌电受到其他肌电活动的影响。 关键词：肌电检测；体表；麻醉；膀胱肌；脉冲串 中图分类号：R365．694；R614．1 文献标识码：A 文章编号：1671 8348(2008)13-1400—02 Experimental research of effect of anaesthesia on recording of electromyographic activity of bladder in rabbit LJU Chao—dong。ZHANG Ming 。GONG Xu (Department of Urology，F rsf Affiliated Hospital，Chongqing University of Medical Sciences，Chongqing 400016，China) Abstract：Objective To observe the effect of anaesthesia on the recording of electromyographic activity of bladder in rabbit and to further understand the effective factors of recording vesical electromyographic activity．Methods Twenty rabbits were randomly divided into 2 groups，with 10 cases in each group．The electrical activity was acquired by use of bipolar electrodes attached simulta— neously vesical wall and abdominal surface of rabbits．Intravesical pressure was recorded with a pressure transducer inserted in the vesical cavity．Correlation analyses and difference comparisons were performed between them after simultaneous recording．Results There were no obviously bursts recorded from either the anaesthesiaed animals during filling period．In micturating period