一次定位多点穿刺法在射频消融治疗大肝癌中的应用_马宽生.pdfVIP

2003 4 9 4 　Chin J Hepatobiliary Surg, Apr 2003, Vol.9, No.4 ·199 · ·· 马宽生　陈敏　黄小兰　 丁钧　董家鸿 【】　　(radio-frequency ablation, RFA) 。　53 70 RFA ; 6.9(5 ～ 10)cm;、CT 、; RFA 、, 。　53 70 RFA 81 , 1.53 。RFA 6 CT , 72.9%。53 12 ～ 18 48(90.5%), 1 70.8%(35/48)。　 RFA 、 。 【】　, ;　;　 One localization and multipoint puncture in treatment of l arge hepatocarcinoma with radiofrequency abl a- t ion MA K uansheng, CHEN Min, HUANG X iaolan, et al .Dep artment of Hepatobiliary S urgery, Southwest Hosp ital, Thir Military Me ical University, Chongqing 400038, P .R .China 【Abstract】　Objective 　T o e plore the application and effect of the method of one localization and multipoint puncture in treatment of large hepatocarcinoma with radiofrequency ablation (RFA).Methods　 Fifty-three cases of large hepatocarcinoma with 70 foci were ablated by RFA with the method of one local- ization and multipoint puncture.The tumor size was the mean 6.9 (5-10)cm in diameter.Hepatic func- tion e amination, alpha-fetoprotein dosage, CT scanning, color ultrasonography and needle biopsy w ere performed.Post-treatment complete necrosis w as evaluated by dynamically enhanced CT scanning and biop- sy .Therapeutic sessions of RFA and complications after RFA were observed and survival time of patients followed up.R esults　The 53 cases of large hepatocarcinoma received RFA for 81 sessions at a rate of 1-3 sessions/per case (mean=1.53 sessions).Complete necrosis of tumor was found in 72.90% of the pa- tients.Forty-eight out of the 53 patients were followed up for 12-18 months after RFA and the 1-year sur- vival rate w as 70.8% (35/48).Conclusions　The method of one localization and multipoint puncture in treatment of large hepatocarcinoma w ith RFA is mini-invasive, safe and notably effective. 【Key words】　Carcinoma, hepatocellular;　Radiofrequency ablation;　Method