白金族金属触媒によるカルボニル化合物の還元アミノ化反.PDFVIP

日本大学文理学部自然科学研究所研究紀要 No.39 （2004）pp.349 385 － 白金族金属触媒によるカルボニル化合物の還元アミノ化反応の研究 矢田　　智 ・高木　　弦 Reductive Amination of Some Carbonyl Compounds Catalyzed by Platinum Metals Satoru YADA and Yuzuru TAKAGI （Received November 20, 2003） The reductive amination of some carbonyl compounds over platinum metals have been studied in ethanol at - - 50 200℃ and the hydrogen pressure of 7 8 MPa to compare the selectivity of these metals for the formation of the primary amine, the secondary amine, the tertiary amine and the alcohol, respectively. In the reductive amination of nonanal, the yield of the primary amine increased in order: Pd Os Pt Rh Ir Ru. A high yield of the primary amine was obtained with Ru (87%), while over Pd the yield was only 24% which was the smallest of the matals investigated. Over Pd and Os catalysts the secondary amine was formed in larger amounts than the primary amine. The yield of primary amine was not increased by the addition of ammoni- um chloride. On the other hand, the formation of the tertiary amine was greatly increased over Pd catalyst from 6% to 45% in the presence of ammonium chloride. - With 2 nonanone, the major product was the corresponding primary amine over platinum metals. In contrast to the results with nonanal, no tertiary amine was found in the products. The secondary amine was also formed not at all (Pd, Ru and Rh) or only to a slight extent (Os), except over Pt and Ir which it was formed in 17% and 12% yields, respectively. Over the catalysts other than Pd, Rh and Ir, the