回生口服液联合化疗治疗中晚期消化道肿瘤患者的效果观察.docVIP

回生口服液联合化疗治疗中晚期消化道肿瘤患者的效果观察 　　郑州人民医院中医科，河南郑州 450000 　　[摘要] 目的 观察回生口服液联合化疗治疗中晚期消化道肿瘤的临床效果。 方法 将73例中晚期消化道肿瘤患者随机分为对照组36例（单纯化疗）和治疗组37例（回生口服液联合化疗），治疗2个周期，观察近期临床疗效、不良反应、生存质量情况。 结果 对照组近期治疗总有效率为25.0%，治疗组为48.6%，两组总有效率比较，差异有统计学意义（P 0.05）。对照组治疗后卡氏评分值有所下降，但治疗前后比较差异无统计学意义（P 0.05）；治疗组治疗后卡氏评分值上升，治疗前后比较，差异有高度统计学意义（P 0.01），两组治疗后组间比较，差异有高度统计学意义（P 0.01）。 结论 回生口服液联合化疗治疗中晚期消化道肿瘤可以提高患者近期疗效，减少不良反应发生率，提高患者生活质量。 　　[关键词] 回生口服液；消化道肿瘤；化疗 　　[中图分类号] R735.7 [文献标识码] A [文章编号] 1673-7210（2014）03（b）-0082-03 　　Clinical efficacy of Huisheng Oral Liquid combined with chemotherapy for advanced digestive neoplasm 　　YAN Fei DOU Chenhui 　　Department of Traditional Chinese Medicine， People′s Hospital of Zhengzhou City， He′nan Province， Zhengzhou 450000， China 　　[Abstract] Objective To evaluate the efficacy of Huisheng Oral Liquid combined with chemotherapy for advanced digestive neoplasm. Methods A total of 73 patients with advanced digestive neoplasm were randomly assigned to receive either chemotherapy alone （control group， n = 36） or Huisheng Oral Liquid combined with chemotherapy （treatment group， n = 37） for 2 cycles. The short-term clinical efficacy， adverse reactions， quality of life in the two groups were compared and analyzed. Results The total effective rate in control group was 25.0% and that in treatment group was 48.6%， there was a significant difference between the two groups （P 0.05）. KPS score of control group was decreased after treatment than that of before， however， there was no significant difference in control group before and after treatment （P 0.05）. KPS score of treatment group was increased after treatment than that of before， the difference of treatment group before and after treatment was obviously significant （P 　　[Key words] Huisheng Oral Liquid； Digestive neoplasm； Chemotherapy 　　消化道肿瘤是目前非常常见的恶性肿瘤，近年发病率逐步上升，病死率高，占全部恶性肿瘤发病率和病死率的50%以上，严重危害人民的生命健康。消化道肿瘤发病早期，以手术治疗为主，及早手术，部分患者可治愈。对于中晚期肿瘤患者，已经丧失手术机会，化疗成为治疗的重要手段。化疗能够抑制肿瘤的复发和转移，但其毒副作用，如消化道反应、骨髓抑制、肝肾毒性等也对机体产生较大的危害，增加患者的