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Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels A novel role in egg production》.pdf
Insect Biochemistry and Molecular Biology 51 (2014) 10e19 Contents lists available at ScienceDirect Insect Biochemistry and Molecular Biology journal homepage: www.els /locate/ibmb Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels: A novel role in egg production a, b c d d Rene Raphemot , Tania Y. Estevez-Lao , Matthew F. Rouhier , Peter M. Piermarini , a, b, e, f, * c, f, * Jerod S. Denton , Julian F. Hillyer a Department of Anesthesiology, Vanderbilt University, Nashville, TN 37232, USA b Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA c Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA d Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA e Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA f Institute for Global Health, Vanderbilt University, Nashville, TN 37232, USA a r t i c l e i n f o a b s t r a c t Article history: Inward rectifier potassium (Kir) channels play essential roles in regulating diverse physiological pro- Received 14 March 2014 cesses. Although Kir channels are encoded in mosquito genomes, their functions remain largely un- Received in revised form known. In this study, we identified the members of the Anopheles gambiae Kir gene family and
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