Methenamine in dairy products by isotope dilution gas chromatography coupled with triple quadrupole mass spectrometry Method validation and occurrence》.pdfVIP

Food Control 57 (2015) 89e95 Contents lists available at ScienceDirect Food Control journal homepage: /locate/foodcont Methenamine in dairy products by isotope dilution gas chromatography coupled with triple quadrupole mass spectrometry: Method validation and occurrence Xing Xu a, b, Xiaoming Zhang a, *, Shabbar Abbas a, Eric Karangwa a, Emmanuel Duhoranimana a, Feijin Peng b, Ping Shu b a State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, PR China b Yunnan Milk and Dairy Products Quality Supervision and Inspection Center, Dali 671000, Yunnan, PR China a r t i c l e i n f o a b s t r a c t Article history: A gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS) method was Received 3 January 2015 developed for the determination of methenamine in dairy products. Methenamine-13C15N isotopic 6 4 Received in revised form reference material was used as an internal standard to quantify the methenamine. The conditions of the 24 March 2015 extraction, solid phase extraction (SPE) and GC-MS/MS were optimized. Linear calibration curves were Accepted 25 March 2015 2 obtained over the cal