Exposure to air pollutants and mortality in hypertensive patients according to demography A 10 year case-crossover study》.pdfVIP

Environmental Pollution 192 (2014) 179e185 Contents lists available at ScienceDirect Environmental Pollution journal homepage: www.else /locate/envpol Exposure to air pollutants and mortality in hypertensive patients according to demography: A 10 year case-crossover study Martin C.S. Wong a, *, Wilson W.S. Tam a, Harry H.X. Wang a, X.Q. Lao a, Daisy Dexing Zhang a, Sky W.M. Chan a, Mandy W.M. Kwan a, Carmen K.M. Fan a, Clement S.K. Cheung b, Ellen L.H. Tong b, N.T. Cheung b, L.A. Tse a, Ignatius T.S. Yu a a JC School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China b Hospital Authority Information Technology Division e Health Informatics Section, Hong Kong, China a r t i c l e i n f o a b s t r a c t Article history: This study evaluated whether short term exposures to NO , O , particulate matter 10 mm in diameter 2 3 Received 7 February 2014 (PM10) were associated with higher risk of mortality. A total of 223,287 hypertensive patients attended Accepted 28 May 2014 public health-care services and newly prescribed at least 1 antihypertensive agent were followed-up for Available online 20 June 2014 up to 5 years. A time-stratified, bi-directional case-crossover design was adopted. For all-cause mortality, significant positive associations were observed for NO2 and PM10 at lag 0e3 days per 10 mg/m3 increase K