Expression level of miR–155 in peripheral blood》.pdfVIP

214 Asian Pacific Journal of Tropical Medicine (2015)214-219 Contents lists available at ScienceDirect IF: 0.926 Asian Pacific Journal of Tropical Medicine journal homepage:/locate/apjtm doi: Document heading 10.1016/S1995-7645(14)60318-7 Expression level of miR-155 in peripheral blood 1△ 1△ 2 1 1 1* Yu-Hui Zhang , Liang-Hua Xia , Jia-Mei Jin , Ming Zong , Ming Chen , Bo Zhang 1Department of Ultrasound, East Hospital Affiliated to Medicine School, Tongji University, Shanghai 200120, China 2Department of Ultrasound, Shanghai Huadong Hospital Affiliated to Medicine School, Fudan University, Shanghai 200040, China ARTICLE INFO ABSTRACT Article history: Objective: To investigate the relationship between the expression level of miR-155 and Received15 December 2014 Received in revised form 20 January 2015 the severity of coronary lesion, and explore the action mechanism. Methods: Peripheral Accepted 15 February 2015 blood mononuclear cells (PBMC) were isolated form blood simple from patients with acute Available online 20 March 2015 myocardial infarction (AMI), unstable angina (UAP), stable angina (SAP) and chest pain syndrome (CPS). RT-PCR was performed to analysis the expression level of miR-155 in Keywords: peripheral blood mononuclear cells, plasma and RAW264.7 macrophagocyte. MTT was used miR-155