冠心病患者血清超敏C-反应蛋白的检测及意义.pdfVIP

湖北省卫生职工医学院学报2004年6月第17卷第2期 ofHubeiMedi豫lStaff n．2004V01．17No．2 Joumal Ju ·l· CoUege 冠心病患者血清超敏C一反应蛋白的检测及意义 朱怀刚 (东南大学临床医学院，江苏南京21o009) [摘要]目的：探讨冠心病患者血清超敏C_反应蛋白(High_Sensitivityc-ReactiveProtein，H孓CRP)的 变化及临床意义。方法：健康对照组300例．冠脉造影组280例。采用胶乳增强比浊法分别测定其H§ CRP的水平。结果：健康对照组H争CRP水平为o．7l±1．28mg／L，呈明显的偏态分布；冠脉造影阳性组 两者差异有统计学意义(Po．01)；冠脉造影阳性组H孓CRP水平随阳性支数增加而升高，且各组问差 异有统计学意义(Po．01，P0．05)。结论：HSCRP水平与冠心病密切相关，其检测对冠心病的预 防及治疗具有重要的临床意义。 [关键词]冠心病；超敏c_反应蛋白；冠脉造影 [中图分类号]R543．32[文献标识码]A ofSerum C—ReactiVe DetectingSignificancehigh—SensitiVity Proteinin HeartDisease Coronary 、ZHU H“以i—g口咒g (SchoolofclinicalMedicine，Southeast 210009，China) University，Nanjing therelations of and thelevelsofserum C_re— [Abstr舵t]obj∞tive：Tostudy significance high_sensitivity active heartdisease(CHD)．Method譬：The1evelsofserumHS_CRP protein(HS_CRP)withcoronary weredetermined enhanced in300 and280 byusingparticle immunonephelometryhealthysubjectsgroup scarification ThelevelsofserumHS-CRPof300 were R髓ults： coronary group． healthysubjectsgroup obvious were differencesbetweenthelevelsofserumHS—CRPin190 asymmetrical；Theresignificant 90 and levelsof coronaryscreeningpositivegroup coronaryscreeningnegativegroup(P：O．01)；The serumHS—CRPwere withthenumberofvessels there