恩度联合化疗治疗晚期非小细胞肺癌的临床研究.pdfVIP

·1560 · MOD ERN ONCOLO GY, A ug20 10 , VO I18,NO 08 恩度联合化疗治疗晚期非小细胞肺癌的临床研究 1 2 1 齐 　瑾 ,殷 　柳 ,郑玉军 Research of endostar com b ined w ith pla tinum - ba sed chem otherapy for advanced non - sm a ll cell lung cancer 1 2 1 Q I J in , Y IN L iu , ZHEN G Yu - jun 1 2 D ep a rtm en t of O ncology, D a lian M un icip a l F riendsh ip H osp ita l, L iaon ing D a lian 116001, Ch ina; D ep a rtm en t of O ncology, F irs t Aff ilia ted H osp ita l of D a lian M ed ica l Un ivers ity, L iaon ing D a lian 1160 11, Ch ina. 【A b stract 】　O bjective: To inve stigate the short - term effects and safety of Endo star ( recomb inant hum an endo sta ) ( ) tin com b ined w ith p latinum - based chemotherap y for advanced non - sm all cell lung cancer N SCLC and to com p are w ith p latinum - based chemotherap y alone. M ethods: Total of 60 advanced N SCLC inp atients were selected and divided into two group s: 28 p atients treated w ith Endo star p lu s p latinum - ba sed chemotherapy and 32 p atients treated w ith p latinum - ba sed chemotherapy alone. A nd the respon se rate ( RR ) , disea se con tro l rate (DCR ) , quality of life imp rovem ent and side reaction s were evaluated. Results: Endo star p lu s cheotherapy comp are to chemotherap y alone, the RR were 28. 57% and 28. 13% ( P 0. 05) ; the DCR were 96. 43% and 93. 75% ( P 0.