812株非结核分枝杆菌临床分离株流行病学特征分析.pdfVIP

2010 12 32 12 # 811 # # # 812 李昕洁 谭守勇 黄业伦 蔡杏珊 刘志辉 ( 510095) : 探讨非结核分枝杆菌的流行病学特征, 为非结核分枝杆菌病防治策略的确立提供 依据 对广州市结核病 部肿瘤防治所2004) 2009 年分枝杆菌培养的实验室资料进行统计 分析 ( 1) 6 年间, 共进行分枝杆菌培养32 906 例, 6 083 例培养阳性其中: 对4 207 例进行了 结核分枝杆菌复合群与非结核分枝杆菌分群, 812 株为非结核分枝杆菌, 占191 3% ( 2) 对558 株非 结核分枝杆菌进行了菌种或复合群鉴定, 种群分布达22 种, 菌种分布前5 的顺位为: 龟-脓肿分枝杆 菌复合群鸟-胞内分枝杆菌复合群偶然分枝菌戈登分枝杆菌和耻垢分枝杆菌( 3) 荷菌者男女比 例约为3B 2, 多为15~ 74 岁患者, 其中15~ 54 岁患者占671 3% 与广州市前10 年相比, 非结 核分枝杆菌临床分离率有上升趋势, 感染人群年龄前移, 且以致病性菌种居多, 值得重视 : 分枝杆菌, 非结核; 流行病学研究 : 刘志辉(liuyixi2005@ 163. com) Analysis on the epidemiological characteristics of 812 non-tuberculous mycobacteria strains Li Xinj i e, Tan Sh ouy ong , Huang Yelun , Ca i Xingshan , Liu Zhih ui Guangzhou Ch est Hosp ita l , Guangz hou 510095, Chin a Abstract: Objective o explore the epidemiological characteristics of non-tuberculous myco- bacterium ( N M) and to provide the basis for the control strategies of N M diseases. Methods Relevant laboratory data from 2004 to 2009 regarding mycobacterial culture and species identifica- tion in Guangzhou uberculosis and Pulmonary umor Control Institute were analyzed retrospec- tively. Results Firstly, 6 083 of 32 906 cases were culture positive during 6 years period, in which 4 207 strains were identified, and 812 strains ( 191 31%) were identified as N M . Secondly, 558 N M strains were performed species identification, in which 22 species or complex were identi- fied. he top five species or complex with the highest occurrence frequency were M . ch clon a e-ab- scessus comp le , M . avi um-in tr acell ulare complex, M .f ortuitum , M . gor d