肿瘤早期检测技术研究现状及必威体育精装版进展.pdfVIP

Chinese Journal of Medical Instrumentation 2012 年36 卷第1 期 综 合 评 述 文章编号 167 1-7 104(20 12)0 1-0043-09 ： 肿瘤早期检测技术研究现状及必威体育精装版进展 【作 者】衣丽婷1 ，刘静1,2* 1 清华大学医学院生物医学工程系，北京，100084 2 中国科学院理化技术研究所，北京，100190 【摘 要】围绕CTC和肿瘤标记物，对肿瘤细胞必威体育精装版检测方法研究以及未来的发展趋势进行了综述。特别剖析了基于肿瘤细胞不同物 理特性进行分离、计数、检测的方法，评估了各自的优缺点，探讨了未来肿瘤早期检测的目标，并阐述了多模式综合检测 这一重要发展方向。 【关 键 词】肿瘤；早期检测；循环肿瘤细胞；生物标记物；物理方法 【中图分类号】R443 【文献标志码】A doi:10.3969/j .issn.1671-7104.2012.01.014 Current Status and Latest Advancement in Developing Techniques for Tumor Early Detection 【Writers 】Yi Liting1, Liu Jing1,2* 1 Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beij ing 100084 2 Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beij ing 100190 【Abstract 】This article is dedicated to present a comprehensive review on the latest progress and future trends in developing detection methods of CTCs and cancer biomarkers. The article especially analyzes the methods to isolate, quantify and detect cancer cells via their distinctively different physical properties. The advantages and disadvantages of different detection approaches are also evaluated. The target towards cancer early detection was discussed. The important direction for developing comprehensive multi-mode detection method was emphasized. 【 】 Key words cancer, early detection, circulating tumor cell, biomarker, physical method 恶性肿瘤如睾丸癌仍可能治愈 但希望大大降低[8] 1 肿瘤现状及早期检测的重要意义 ， 。 由此看来 早期诊断和治疗对于提升肿瘤病人生存率 近年来 恶性肿瘤已成为全球范围内严重危害 ， ， 具有至关重要的