消化系统恶性肿瘤放化疗前后血浆D二聚体和血浆癌胚抗原变化及临床意义.pdfVIP

· ·144· ·论著· 消化系统恶性肿瘤放化疗前后血浆D一二聚体 与血浆癌胚抗原变化及临床意义 张美云，李晓凤，刘芹 (内蒙古自治区包头市肿瘤医院内二科．014030) [摘要] 目的 探讨消化道恶性肿瘤患者化疗前后血浆D-二聚体及血清癌胚抗原的临床意义。方法 测定63例消化道恶性肿瘤化疗前后血浆D-二聚体浓度及癌胚抗原浓度。结果化疗后疗效达完全缓解 二聚体阳性率66．67％，CEA阳性率60％；化疗后疗效进展(PD)组血浆D·二聚体阳性率78．57％，CEA阳性 率64．29％。三组间比较，D．二聚体有差异PO．05，CEA有差异P0．05。结论测定消化系统恶性肿瘤患 者血浆D．二聚体有助评估临床放化疗效果。 [关键宇】 消化系统肿瘤；脱氧核糖核酸酶(嘧啶二聚体)；诊断技术，消化系统 [中图分类号】R735 [文献标识码]A [文章编号]1672-6790(2009)02-0144-02 andafter and andclinical ofblood D-dilnerbefore Changes significanceplasnm radiotherapychemotherapy in tllmorZHANG patients1vi恤digestivesystemmalignant Mei-yun，uXiao-feng，HUQin(DepartmentofInter- halMedicine II，CancerHospitalofBaotou，Baotou014030，China) Todiscusstheclinical ofblood D-dimerbofo陀 [Abstract]Objective significanceregardingchange plasma andafter and in with tumor．Methods patientsdigestivesystemmalignant UsingHong radiotherapychemot}Ierapy to on103 VNIONHONESTunitetheimmune Kong enzyme adsorption(fixedquantity)testingbox，D-dimerdensity measuredbeforeand with tumorwere afterthe treatment．Results digestivesystemmalignant chemotherapy patients ．Therewas differenceinblood D—dimerbetweenthe of tumormetastasis significant plasma groupdigestivesystem valueshowed differentbeforeandafter andthatofnotmetastasized．TheD-dimer group significant chemotherapy．