幽门螺杆菌感染与胃肠外疾病的关系高文.pdfVIP

( ) 2007 6 28 6 335 ¹ ¹ 高 文 胡伏莲 : 流行病学研究显示幽门螺杆菌可能与某些胃肠外疾病发生有关, 除治疗可能缓解缺 铁性贫血ITP酒糟鼻等疾病的临床症状和实验室异常从粥样硬化相关心血管疾病血液 系统疾病皮肤病的研究结果看, 尽管有证据显示该类疾病患者幽门螺杆菌感染率高于普通 人群, 但二者是因果还是伴随现象仍不得而知, 同时尚无 除治疗远期效果的报道对相关 胃肠外疾病是否需要进行幽门螺杆菌检测和治疗尚无定论鉴于流行病学研究的局限性和 发病机制的不确定性, 对二者关系应持慎重态度, 避免对幽门螺杆菌检测和 除治疗的过度 滥用二者关系的阐明有待机制研究的进展 : 幽门螺杆菌, 胃肠外疾病, 机制 : R573. 3 :A : 1002- 0772(2007) 06- 0017- 04 Helicobacter pylori Infection and Extragastic Diseases GA O Wen , H U F u-lian . P eking Un iv er sity F irst H osp ital , B eij ing 100034, Ch ina Abstract: Epidemiological data ave s own t at t ere are maybe some connection betw een Helicobacter pylori infection and some extragas- tric diseases, and t e eradication t erapy mig t release t e symptoms and lab abnormalities of some diseases suc as iron deficiency anemia, ITP and brandy nose. It was reported t at t e prevalence of Helicobacter pylori infection in patients wit at erosclerosis, ematological and dermatologic diseases was significantly ig er t an t at in population. But we didn. t know it is cause- effect or just sync ronization. And t ere were no study on t e long- term follow - up of t e effect of eradication t erapy. We s ould avoid t e abuseof Helicobacter pylori de- tection and eradication indications. T e study on t e mec anism may be elpful. Key Words: Helicobacter pylori, extragastric disease, mec anism , (Helicobacter pylori, Hp) 1994 Mendall ,