出声阅读条件下不规则汉字频率效应的功能磁共振成像研究.pdfVIP

维普资讯 中国医学影像技术2004年第 鲞笙 塑 ! g!旦g!!!旦!!： ：!! ：! ·1639 · 防脑功能磁共振成像 FrequencyeffectinreadingaloudirregularChinesecharacters： an fM RIstudy TAN Xiang-jie，MALi一 ，yUWei，ZHANGZhao—qi，WANG Xiao—yi，WENG Xu—chu (InstituteofPsychology，ChineseAcademyofSciences，Beijing100101，China) [Abstract- Objective TocharacterizebrainactivationassociatedwiththeeffectsoffrequencyinreadingaloudofChinese charactersusingevent-relatedfunctionalmagneticresonanceimaging．Methods Eightuniversitystudentswereinstructedto overtlvreadvisua11ypresentedChinesecharacterswhilebeingscannedwitha1．5TM RISiemensscanner．Twentyhighand twentylow frequencyirregularcharacterswereused．Results Frequencyeffectwasobserved intheleftmiddlefrontalgY— rus．1eftinferiorfrontalgyrus，supplementarymotorarea，leftposteriortemporalgyrus，leftinsula，anteriorcingulatecor— tex，andbilateralextrastriateareas．Activationintheseregionswassignificantlystrongerduringreading low frequencyir— regularcharactersthanreadinghighfrequencyirregularcharacters．Conclusion OvertlyreadingChinesecharacters，particu— larlylow frequencyirregularcharacters，canreliablyelicitmostlanguageregions．Thistask thusisfeasibleforclinicalUS— age．AnteriorclngulatedcortexandleftmiddlefrontallobeappeartobespecificallyrelatedtoreadingofChinesecharacters． [Keywords] Functionalmagneticresonanceimaging；Readingaloud；Chinesecharacter；Frequencyeffect；Anteriorcingulate 出声阅读条件下不规则汉字频率效应的功能磁共振成像研究 谭向杰 ，马力飞 ，于 薇 ，张兆琪。，王晓怡 ，翁旭初 (1．中国科学院心理研究所，北京 100101；2．首都医科大学附属安贞医院) [摘 要] 目的 利用事件相关功能磁共振成像技术观察出声阅读条件下不规则汉字频率效应的脑激活模式。方法 8 名非语言专业大学生在MR扫描过程中执行汉字出声阅读任务。用视觉方式随机呈现 4O个形声字，其中高频、低频不规 则字各 2o个。结果 左侧额中回、左侧额下回、辅助运动区、左侧颞下回后部、双侧纹外皮层、