空间生物反应器研究进展与策略.pdfVIP

23 5 Vol. 23 No. 5 2010 10 SpaceM ed icine M ed ical Engineering Oct. 2010 空间生物反应器研究进展与策略* 1 1 1 1 2 1 郑 森 , 王 超, 李 春, 邓玉林 , 蒋远大, 李艳菊 ( 1. , 100081; 2. , 100190) : 空间生物反应器是人类利用空间资源进行空间生物学与空间生物技术研究的重要硬件设备, 其应 用为空间生 科学研究提供了必要的生物材料, 如细胞组织和微生物等本文针对空间生物反应器对 空间生物学和空间生物技术的重要作用, 综述了空间生物反应器的研制发展历程和现状, 并对灌流式中 的旋转壁式生物反应器细胞培养单元反应器单环路细胞培养反应器微型连续培养反应器和非灌流 式中的多层逆流细胞培养反应器新型膜生物反应器等空间生物反应器的主体结构和工作原理做了介 绍最后, 对空间生物反应器的发展趋势进行了分析和展望 : 微重力; 空间生物学; 空间生物反应器 : Q693 : A : 2010) R esearch Progresses and S trateg ies of Spa ce B ioreactor. ZHENG Sen, WANG Chao, IChun, DENG Yu lin, JIANG Yuanda, IYanju. SpaceMedicine M edical Engineering, 2010, 23( 5): 386~ 390 Abstract: Space bioreactor is an mi portant device that canmake good use of space resources for space biology and space biotechnology research. Space bioreactor supported the research of the space biologyw ith cel,l tis sue andm icrobe. Considering the mi portance and necessity of the space bioreactor for space biology and space biotechnology, this paper presented a review on the research progresses of space bioreactor, and made a de tailed introduction about them ain structure and operation principle of the perfusion bioreactor, including rota ting wall vessel bioreactor, cell culture unit bioreactor, single loop for cell culture bioreactor, m iniature long term cell culture bioreactor, and nonperfusion bioreactor, including counter sheetflow sandw ich cell culture bioreactor, novel membrane bioreactor. finally, The development and prospect of space bioreactor was ana lyzed. Keywords: m icrogravity; space biology; space bioreactor Address reprint requests to: I Chun. School of ife Science, Beijing Institute of Technology, Beijing 100081, China ,