Femoxetine-hydrochloride-FG4963-生命科学试剂-MCE.pdf

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Femoxetinehydrochloride

Cat.No.:HY-106644A

CASNo.:56222-04-9

Synonyms:FG4963

分⼦式:C₂₀H₂₆ClNO₂

分⼦量:347.88

作⽤靶点:5-HTReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Femoxetinehydrochloride是⼀种具有抗抑郁特性的⾎清素(5-HT)抑制剂。Femoxetinehydrochloride通过

阻⽌⾎清素被神经细胞重新吸收，导致神经递质在突触间隙中的浓度增加，从⽽增强了⾎清素的信号传递来增

加⼤脑中的⾎清素⽔平。Femoxetinehydrochloride可⽤于研究⾎清素在抑郁症和其他情感障碍中的作⽤，以

及5-HT再摄取抑制剂如何影响情绪和⾏为[1][2]。

REFERENCES

[1].BechgaardE,etal.Hepaticeliminationoffemoxetineinpig[J].ActaPharmacologicaetToxicologica,1983,52(1):1-7.

[2].LundJ,etal.Pharmacokineticsoffemoxetineinman[J].ActaPharmacologicaetToxicologica,1979,44(3):177-184.

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