底板反应蛋白(SPON1)对骨肉瘤转移的影响及机制研究-外科学专业论文.docx

万方数据 万方数据 目 录 中文摘要·················································································1 英文摘要·················································································7 英文缩写···············································································16 研究论文 底板反应蛋白(SPON1)对骨肉瘤转移的影响及机制研究 引言·····················································································18 第一部分 探讨SPON1是否为人转移性骨肉瘤和人非转移性骨肿瘤的差 异表达基因 前言···············································································20 材料与方法······································································21 结果···············································································28 附图···············································································30 附表···············································································35 讨论···············································································37 小结···············································································40 参考文献·········································································41 第二部分 探讨SPON1在骨肉瘤细胞和体内肿瘤迁移和侵袭中的作用 前言 46 材料与方法······································································48 结果···············································································56 附图···············································································59 讨论···············································································70 小结···············································································73 参考文献·········································································74 第三部分 探讨骨肉瘤细胞中SPON1与FAK\Src信号通路关系 前言 77 材料与方法······································································78 结果···············································································84 附图···············································································87 讨论···········································································